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CAS 56390-08-0

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5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-

Description:
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), with CAS number 56390-08-0, is a complex organic compound characterized by its naphthacene structure, which is a polycyclic aromatic hydrocarbon. This substance features multiple functional groups, including hydroxyl (-OH), methoxy (-OCH3), and an acetyl group, contributing to its potential biological activity. The presence of the amino sugar moiety suggests that it may exhibit properties relevant to medicinal chemistry, possibly influencing its solubility and interaction with biological systems. The hydrochloride form indicates that it is a salt, which can enhance its stability and solubility in aqueous environments. This compound may be of interest in pharmaceutical research, particularly for its potential applications in drug development or as a biochemical probe. Its stereochemistry, indicated by the (8S,10S) designation, suggests specific spatial arrangements that could be crucial for its biological activity.
Formula:C27H29NO10·ClH
InChI:InChI=1/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22-,27-;/m0./s1
InChI key:InChIKey=GUGHGUXZJWAIAS-RBSGUPIDSA-N
SMILES:OC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C[C@@](C(C)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=C(OC)C=CC5.Cl
Synonyms:
  • (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside hydrochloride
  • (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxynaphthacene-5,12-dione hydrochloride
  • 4′-Epidaunorubicin hydrochloride
  • 4′-epi-Daunomycin hydrochloride
  • 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-
  • 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S,10S)-
  • 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-
  • NSC 249333
  • 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-
  • 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S,10S)-
  • See more synonyms
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Found 1 products.
  • 4'-Epidaunorubicin hydrochloride
    Biosynth
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    4'-Epidaunorubicin hydrochloride

    CAS:
    <p>4'-Epidaunorubicin hydrochloride is an anthracycline antibiotic derivative, which is synthesized from modifications of natural products. It functions as a topoisomerase II inhibitor, which intercalates into DNA strands and disrupts replication and transcription, thereby inhibiting cancer cell proliferation. This compound is primarily utilized in the field of oncology for its potent anti-tumor activities. By forming stable complexes with DNA and topoisomerase II, 4'-Epidaunorubicin hydrochloride induces breaks in the DNA strands, leading to apoptosis of cancer cells. It is often used in treatment protocols for various malignancies, including leukemia and solid tumors. While highly effective, its administration is carefully managed to mitigate potential cardiotoxicity, a common attribute of anthracycline drugs. Research continues to explore its full potential and optimize delivery methods to enhance its therapeutic index.</p>
    Formula:C27H30ClNO10
    Purity:Min. 95%
    Molecular weight:563.98 g/mol

    Ref: 3D-AE16714

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