CAS 56392-18-8

Metoprolol hydrochloride

Description:

Metoprolol hydrochloride is a selective beta-1 adrenergic antagonist, commonly used in the treatment of hypertension, angina pectoris, and heart failure. It is a white to off-white crystalline powder that is soluble in water and methanol, but practically insoluble in organic solvents like chloroform and ether. The substance has a molecular formula of C15H25N O3S·HCl, indicating the presence of a sulfonamide group, which contributes to its pharmacological activity. Metoprolol hydrochloride works by blocking beta-1 receptors primarily located in the heart, leading to decreased heart rate and myocardial contractility, ultimately reducing cardiac workload and oxygen demand. Its pharmacokinetics include rapid absorption and extensive first-pass metabolism, resulting in variable bioavailability. The drug is typically administered orally, and its dosage may vary based on the condition being treated. As with any medication, potential side effects can include fatigue, dizziness, and bradycardia, necessitating careful monitoring during treatment.

Formula: C₁₅H₂₅NO₃·ClH

InChI: InChI=1S/C15H25NO3.ClH/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;/h4-7,12,14,16-17H,8-11H2,1-3H3;1H

InChI key: InChIKey=UKBBZNRSHOCRNP-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=CC=C(CCOC)C=C1.Cl

Synonyms:

• 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1)
• Metoprolol hydrochloride
• 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride
• 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride, (±)-

Metoprolol HCl

CAS: 56392-18-8

Metoprolol: a β1 blocker for high blood pressure, chest pain, fast heart rate, post-heart attack care, and migraine prevention.

Formula: C₁₅H₂₆ClNO₃

Color and Shape: Solid

Molecular weight: 303.827

Ref: TM-T71800