CAS 564-16-9: 11-Deoxyglycyrrhetinic acid

Description: 11-Deoxyglycyrrhetinic acid is a triterpenoid compound derived from glycyrrhizin, which is found in the root of the licorice plant (Glycyrrhiza glabra). It is characterized by its molecular structure, which includes a pentacyclic triterpene skeleton. This compound exhibits anti-inflammatory, anti-viral, and anti-cancer properties, making it of interest in pharmacological research. Its mechanism of action is often linked to the inhibition of certain enzymes and pathways involved in inflammation and cell proliferation. 11-Deoxyglycyrrhetinic acid is also known for its ability to modulate the immune response and has been studied for its potential therapeutic applications in conditions such as hepatitis and other viral infections. In terms of physical properties, it is typically a white to off-white crystalline powder, soluble in organic solvents but less so in water. Safety data indicates that it should be handled with care, as with many bioactive compounds, due to potential side effects and interactions.

Formula: C₃₀H₄₈O₃

InChI: InChI=1S/C30H48O3/c1-25(2)21-10-13-30(7)22(28(21,5)12-11-23(25)31)9-8-19-20-18-27(4,24(32)33)15-14-26(20,3)16-17-29(19,30)6/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,26+,27-,28-,29+,30+/m0/s1

InChI key: InChIKey=JZFSMVXQUWRSIW-BTJIZOSBSA-N

SMILES: O=C(O)C1(C)CCC2(C)CCC3(C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1)C

Synonyms:

• 11-Deoxoglycyrrhetinic acid
• Olean-12-en-30-oic acid, 3β-hydroxy-
• (3β,20β)-3-Hydroxyolean-12-en-29-oic acid
• (3beta,20beta)-3-Hydroxy-olean-12-en-29-oic acid
• (3beta,18alpha)-3-hydroxyolean-12-en-29-oic acid
• 11-Deoxo-18β-glycyrrhetic acid
• Olean-12-en-29-oic acid, 3-hydroxy-, (3β,20β)-

DG 381B

CAS: 564-16-9

DG 381B (11-Deoxyglycyrrhetinic acid) has anti-inflammatory and potential anticancer activity, inhibiting tumor formation in nude …

• Formula: C₃₀H₄₈O₃
• Color and Shape: Soild
• Molecular weight: 456.7