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CAS 564-36-3

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Ergocornine

Description:
Ergocornine is a naturally occurring alkaloid derived from the ergot fungus, specifically from the species Claviceps purpurea. It is part of the larger group of ergot alkaloids, which are known for their complex structures and diverse biological activities. Ergocornine is characterized by its tetracyclic structure, which includes a fused indole and isoquinoline framework. This compound exhibits various pharmacological properties, including vasoconstriction and effects on neurotransmitter systems, particularly in relation to serotonin and dopamine. Ergocornine has been studied for its potential therapeutic applications, including its role in treating migraines and other vascular disorders. However, it is also associated with adverse effects, particularly when derived from contaminated grains, leading to ergotism. The compound is typically found in a crystalline form and is soluble in organic solvents. Its chemical properties and biological activities make it a subject of interest in both pharmacology and toxicology. As with many alkaloids, safety and dosage considerations are crucial when exploring its applications.
Formula:C31H39N5O5
InChI:InChI=1/C31H39N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,12,14,16-17,19,23-24,26,32,40H,7,10-11,13,15H2,1-5H3,(H,33,37)/t19-,23-,24+,26+,30-,31+/m1/s1
InChI key:InChIKey=UJYGDMFEEDNVBF-OGGGUQDZSA-N
SMILES:O[C@]12N(C(=O)[C@@](NC(=O)[C@@H]3C=C4C=5C=6C(C[C@]4(N(C)C3)[H])=CNC6C=CC5)(C(C)C)O1)[C@@H]([C@@H](C)C)C(=O)N7[C@]2(CCC7)[H]
Synonyms:
  • Ergocornine
  • Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′,5′-bis(1-methylethyl)-, (5′α)-
  • Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv.
  • 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv.
  • (5′α)-12′-Hydroxy-2′,5′-bis(1-methylethyl)ergotaman-3′,6′,18-trione
  • 12′-Hydroxy-2′,5′-α-bis(1-methyl-ethyl)ergotaman-3′,6′,18-trion
  • ERGOCORNINE >95% DOPAMINE RECEPTOR AGO
  • ergocornin
  • (5'alpha)-12'-Hydroxy-2',5'-bis(1-methylethyl)ergotaman-3',6',18-trione
  • 12'-HYDROXY-2',5'-ALPHA-BIS(1-METHYL-ETHYL)ERGOTAMAN-3',6',18-TRIONE
  • See more synonyms
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Found 6 products.
  • Ergocornine
    Targetmol
    + Info

    Ergocornine

    CAS:
    Ergocornine is a naturally occurring ergot alkaloid and acts as a dopamine receptor (dopamine receptor) agonist.
    Formula:C31H39N5O5
    Color and Shape:Solid
    Molecular weight:561.67

    Ref: TM-TN8447

  • Ergocornine
    Doctor Ehrenstorfer
    + Info

    Ergocornine

    Controlled Product
    CAS:
    Formula:C31H39N5O5
    Color and Shape:Neat
    Molecular weight:561.67

    Ref: 04-C13201200

    500µg
    339.00€
  • N-Nitroso Ergocorninine
    TLC
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    N-Nitroso Ergocorninine

    CAS:
    Formula:C31H38N6O6
    Molecular weight:590.68

    Ref: 4Z-E-185002

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Ergocornine
    TLC
    + Info

    Ergocornine

    CAS:
    Formula:C31H39N5O5
    Molecular weight:561.68

    Ref: 4Z-E-220001

    5mg
    To inquire
    10mg
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    25mg
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    50mg
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    100mg
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  • Ergocornine
    TRC
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    Ergocornine

    Controlled Product
    CAS:
    <p>Applications Ergocornine is a natural ergot alkaloid derived from lysergic acid. Ergocornine is a component of Ergotoxine. Ergocornine is isolated from Ergot.<br>References Bhat, R., et al.: Toxicol. Appl. Pharmacol., 36, 11 (1976), Komarova, E., et al.: Pharm. Chem. J., 35, 542 (2001), Krska, R., et al.: Anal. Bioanal. Chem., 391, 563 (2008), Frenich, A., et al.: Food Chem., 117, 705 (2009),<br></p>
    Formula:C31H39N5O5
    Color and Shape:Neat
    Molecular weight:561.67

    Ref: TR-E597350

    25mg
    49,815.00€
  • Ergocornine
    Biosynth
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    Ergocornine

    Controlled Product
    CAS:
    <p>Ergocornine is an ergoline alkaloid, which is a naturally occurring compound found in ergot fungi, specifically Claviceps species. These fungi predominantly infect cereal grains such as rye, leading to the production of a variety of ergot alkaloids. Ergocornine acts mainly by interacting with adrenergic receptors, displaying affinity for both alpha-adrenergic and serotonin receptor subtypes. This interaction results in vasoconstrictive and neuromodulatory effects, primarily impacting vascular and smooth muscle tissues.Ergocornine and related alkaloids have been studied extensively for their pharmacological properties. They are of particular interest due to their potential applications in treating conditions such as migraines, where the vasoconstrictive properties can mitigate the symptoms. Additionally, their effects on smooth muscles make them candidates for research in uterine contraction regulation during labor. However, due to the potent nature of these compounds and potential for toxicity, their clinical applications require careful consideration of dosage and delivery systems. Scientists continue to explore ergocornine's pharmacodynamics to better understand its therapeutic potential and safety profile.</p>
    Formula:C31H39N5O5
    Purity:Min. 95%
    Molecular weight:561.67 g/mol

    Ref: 3D-FE30655

    50mg
    10,560.00€