CAS 56413-94-6

N,2-Didehydro-1,4-dideoxy-1,2-dihydro-4-[(2R)-2-[(S)-1-hydroxyethyl]-1-pyrrolidinyl]-1-oxorifamycin

Description:

N,2-Didehydro-1,4-dideoxy-1,2-dihydro-4-[(2R)-2-[(S)-1-hydroxyethyl]-1-pyrrolidinyl]-1-oxorifamycin, with CAS number 56413-94-6, is a synthetic derivative of rifamycin, a class of antibiotics known for their efficacy against bacterial infections, particularly tuberculosis. This compound features a complex molecular structure characterized by multiple functional groups, including a pyrrolidine ring and a hydroxyethyl substituent, which contribute to its biological activity. The presence of the didehydro and dideoxy modifications enhances its pharmacological properties, potentially improving its ability to penetrate bacterial cell walls and inhibit RNA synthesis. As with other rifamycins, it is expected to exhibit broad-spectrum antibacterial activity, although specific efficacy and safety profiles would depend on further pharmacological studies. The compound's unique structural features may also influence its solubility, stability, and metabolic pathways, making it a subject of interest in medicinal chemistry and antibiotic development.

Formula: C₄₃H₅₆N₂O₁₂

Synonyms:

• Rifamycin, N,2-didehydro-1,4-dideoxy-1,2-dihydro-4-[(2R)-2-[(1S)-1-hydroxyethyl]-1-pyrrolidinyl]-1-oxo- (9CI)
• Halomicin D
• N,2-Didehydro-1,4-dideoxy-1,2-dihydro-4-[(2R)-2-[(S)-1-hydroxyethyl]-1-pyrrolidinyl]-1-oxorifamycin

Halomicin D

CAS: 56413-94-6

Halomicin D is an ansamycin-class antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria.

Formula: C₄₃H₅₆N₂O₁₂

Color and Shape: Solid

Molecular weight: 792.911

Ref: TM-TN10107