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CAS 56420-45-2

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Epirubicin

Description:
Epirubicin is an anthracycline antibiotic and chemotherapeutic agent primarily used in the treatment of various cancers, including breast cancer and bladder cancer. It is a derivative of doxorubicin, designed to enhance efficacy while reducing some of the side effects associated with its parent compound. Epirubicin functions by intercalating into DNA, disrupting the replication process, and inducing apoptosis in rapidly dividing cancer cells. Its chemical structure features a tetracyclic ring system, which is characteristic of anthracyclines, and it contains hydroxyl and methoxy functional groups that contribute to its pharmacological properties. The substance is typically administered intravenously and is known for its potential cardiotoxicity, necessitating careful monitoring of cardiac function during treatment. Epirubicin is often used in combination with other chemotherapeutic agents to improve treatment outcomes. Its effectiveness, along with its side effect profile, makes it a critical component in oncological therapy regimens.
Formula:C27H29NO11
InChI:InChI=1/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15+,17-,22-,27?/m1/s1
InChI key:InChIKey=AOJJSUZBOXZQNB-VTZDEGQISA-N
SMILES:OC=1C2=C([C@@H](O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C[C@@](C(CO)=O)(O)C2)C(O)=C4C1C(=O)C=5C(C4=O)=C(OC)C=CC5
Synonyms:
  • (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • 4'-Epi-DX
  • 4'-Epiadriamycin
  • 4'-Epidoxorubicin
  • 4'-epi-Adriamycin
  • 4'-epi-Doxorubicin
  • 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
  • 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
  • 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
  • 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
  • See more synonyms
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Found 4 products.