The chemical substance known as a tubulin polymerization inhibitor, with the CAS number 564468-51-5, is primarily recognized for its role in disrupting the normal function of tubulin, a protein that is essential for microtubule formation in cells. This inhibition can interfere with various cellular processes, including mitosis, making it a subject of interest in cancer research and treatment. Typically, such inhibitors exhibit a high affinity for the tubulin protein, preventing its polymerization into microtubules, which can lead to cell cycle arrest and apoptosis in rapidly dividing cells. These compounds often possess specific structural features that allow them to bind effectively to the tubulin dimer, and their efficacy can be influenced by factors such as solubility, stability, and the presence of functional groups. Additionally, they may exhibit varying degrees of selectivity and potency, which are critical for their therapeutic applications. Overall, tubulin polymerization inhibitors represent a significant class of compounds in the development of anti-cancer therapies and other medical applications.

tubulin polymerization inhibitor

564468-51-5: The chemical substance known as a tubulin polymerization inhibitor, with the CAS number 564468-51-5, is primarily recognized for its role in disrupting the normal function of tubulin, a protein that is essential for microtubule formation in cells. This inhibition can interfere with various cellular processes, including mitosis, making it a subject of interest in cancer research and treatment. Typically, such inhibitors exhibit a high affinity for the tubulin protein, preventing its polymerization into microtubules, which can lead to cell cycle arrest and apoptosis in rapidly dividing cells. These compounds often possess specific structural features that allow them to bind effectively to the tubulin dimer, and their efficacy can be influenced by factors such as solubility, stability, and the presence of functional groups. Additionally, they may exhibit varying degrees of selectivity and potency, which are critical for their therapeutic applications. Overall, tubulin polymerization inhibitors represent a significant class of compounds in the development of anti-cancer therapies and other medical applications.

Tubulin Polymerization Inhibitor

<p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>

CAS 564468-51-5

tubulin polymerization inhibitor

Tubulin Polymerization Inhibitor

Ref: TR-T897138

Tubulin polymerization-IN-24

Ref: TM-T60936