CAS 565-20-8: Monoacetyldapsone
Description:Monoacetyldapsone, with the CAS number 565-20-8, is a chemical compound that belongs to the class of sulfonamides, which are known for their antibacterial properties. It is a derivative of dapsone, featuring an acetyl group that enhances its pharmacological profile. This compound typically appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. Monoacetyldapsone exhibits antimicrobial activity, particularly against certain bacteria, making it relevant in the treatment of various infections, including those caused by Mycobacterium leprae, the causative agent of leprosy. The compound's mechanism of action involves the inhibition of folate synthesis in bacteria, which is crucial for their growth and replication. Additionally, it may have anti-inflammatory properties, contributing to its therapeutic applications. As with many sulfonamides, caution is advised regarding potential allergic reactions and side effects, which can include skin rashes and hematological issues.
Formula:C14H14N2O3S
InChI:InChI=1S/C14H14N2O3S/c1-10(17)16-12-4-8-14(9-5-12)20(18,19)13-6-2-11(15)3-7-13/h2-9H,15H2,1H3,(H,16,17)
InChI key:InChIKey=WDOCBIHNYYQINH-UHFFFAOYSA-N
SMILES:O=C(NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(N)C=C2)C
- Synonyms:
- 4'-Sulfanilylacetanilide
- 4-Acetamido-4′-aminodiphenyl sulfone
- 4-Acetamidophenyl 4′-aminophenyl sulfone
- 4-Acetylamino-4′-aminodiphenyl sulfone
- 4-Acetylamino-4′-aminophenyl sulfone
- 4-Amino-4′-acetamidodiphenyl sulfone
- Acetamide, N-(4-((4-aminophenyl)sulfonyl)phenyl)-
- Acetamide, N-(4-((4-aminophenyl)sulfonyl)phenyl)- (9CI)
- Acetanilide, 4'-sulfanilyl-
- Acetyldapsone
- See more synonyms
- Brn 2746651
- Ccris 5693
- Madds
- Monoacetyldapsone
- N-(4-((4-Aminophenyl)sulfonyl)phenyl)acetamide
- N-Acetyl-4,4'-diaminodiphenylsulfone
- N-Acetyldapsone
- Nsc 27184
- 3-13-00-01286 (Beilstein Handbook Reference)
- n-(4-((4-aminophenyl)sulfonyl)phenyl)-acetamid
- N-Acetyl[4,4'-sulfonylbis(aniline)]
- ACETYL DAPSONE
- 4’-sulfanilyl-acetanilid
- N-acetyle Dapsone D8
- Dapsone N-Acetyl Impurity/ Monoacetyl Dapsone
- N-Acetyldapsone solution in Methanol, 1000ug/mL
- N-Acetyldapsone, MADDS
- MONO-N-ACETYL-4,4'-SULFONYLBISBENZENEAMINE
- Monoacetyldapson
- Dapsone N-Acetyl Impurity
- N-MONOACETYL-4,4'-DIAMINODIPHENYL SULFONE
- MONOACETYL DAPSONE
- Dapsone Impurity 2（Monoacetyl Dapsone）
- N-[4-(4-azanylphenyl)sulfonylphenyl]ethanamide
