CAS 565-33-3

3-Amino-N-[(cyclohexylamino)carbonyl]-4-methylbenzenesulfonamide

Description:

3-Amino-N-[(cyclohexylamino)carbonyl]-4-methylbenzenesulfonamide, with the CAS number 565-33-3, is a sulfonamide compound characterized by the presence of an amino group, a sulfonamide functional group, and a cyclohexylamino substituent. This compound typically exhibits properties associated with sulfonamides, such as antibacterial activity, due to its ability to inhibit bacterial folic acid synthesis. It is generally soluble in polar solvents and may have limited solubility in non-polar solvents. The presence of the cyclohexyl group contributes to its hydrophobic characteristics, while the sulfonamide moiety enhances its interaction with biological targets. The compound's structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. Additionally, it may exhibit specific reactivity patterns typical of amines and sulfonamides, making it a candidate for further chemical modifications. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity and environmental impact.

Formula: C₁₄H₂₁N₃O₃S

InChI: InChI=1/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18)

InChI key: InChIKey=XXYTXQGCRQLRHA-UHFFFAOYSA-N

SMILES: S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC(N)=C(C)C=C2

Synonyms:

• 1-(3-Amino-p-tolylsulfonyl)-3-cyclohexylurea
• 1-(3-Aminotosyl)-3-Cyclohexylurea
• 3-Amino-4-methylbenzenesulfonylcyclohexylurea
• 3-Amino-N-[(cyclohexylamino)carbonyl]-4-methylbenzenesulfonamide
• 3-amino-N-(cyclohexylcarbamoyl)-4-methylbenzenesulfonamide
• Benzenesulfonamide, 3-amino-N-[(cyclohexylamino)carbonyl]-4-methyl-
• Euglycin
• Glyhexylamide
• Glyhexylamine isodiane
• Melanex
• Methahexamide
• Methexamide
• N-Cyclohexyl-N′-(3-amino-4-methylbenzenesulfonyl)urea
• S 1600
• Urea, 1-cyclohexyl-3-(4-methylmetanilyl)-
• Wp 40
• metahexamide
• 1-(3-amino-4-methyl-phenyl)sulfonyl-3-cyclohexyl-urea
• 1-(3-azanyl-4-methyl-phenyl)sulfonyl-3-cyclohexyl-urea
• Metahexanamide
• Melonex

Metahexamide

Controlled Product

CAS: 565-33-3

Applications Metahexamide is used in biological studies to evaluate the elevation of blood urea nitrogen level in dogs and human subjects by administering chloral hypnotics.
References Wieg, H., Am. J. Med. Tech., 26, 11 (1960);

Formula: C₁₄H₂₁N₃O₃S

Color and Shape: Neat

Molecular weight: 311.40

Ref: TR-M225600

Metahexamide

CAS: 565-33-3

3-Amino-4-Methylbenzenesulfonylcyclohexylurea (3AMBC) is a drug that is used to treat metabolic disorders, autoimmune diseases, and other conditions. 3AMBC inhibits the production of free fatty acids by binding to the enzyme acyl-CoA synthetase 2 (ACS2). The bound form of 3AMBC has been shown to have a higher affinity for ACP2 than the free form, which may account for its strong inhibition of fatty acid synthesis. 3AMBC also has anti-inflammatory properties and has been shown to inhibit the production of inflammatory cytokines in mice with collagen-induced arthritis. This drug also binds to neutrophils and macrophages, which may account for its anti-inflammatory effects. 3AMBC is an antidiabetic agent that increases glucose uptake in liver cells and improves glucose tolerance in diabetic patients. It also inhibits the release of glucose from the liver into the bloodstream by

Formula: C₁₄H₂₁N₃O₃S

Purity: Min. 95%

Molecular weight: 311.4 g/mol

Ref: 3D-FA61379