CAS 565452-98-4

2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)

CAS: 565452-98-4

Formula: C₇H₉ClN₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 172.6122

Ref: IN-DA00EFAJ

Vildagliptin Impurity 12

CAS: 565452-98-4

Formula: C₇H₉ClN₂O

Color and Shape: Off-White Solid

Molecular weight: 172.61

Ref: 4Z-V-2219

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

Controlled Product

CAS: 565452-98-4

Applications (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);

Formula: C₇H₉ClN₂O

Color and Shape: Neat

Molecular weight: 172.61

Ref: TR-C363785

Vildagliptin Chloroacetyl Nitrile (R)-Isomer

CAS: 565452-98-4

Formula: C₇H₉ClN₂O

Molecular weight: 172.61

Ref: ST-EA-CP-V1003