CAS 56559-62-7

1-methyl-1H-indole-3-carbohydrazide

Description:

1-Methyl-1H-indole-3-carbohydrazide is an organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features a hydrazide functional group, which is indicative of its potential reactivity and biological activity. It typically appears as a solid and is soluble in various organic solvents. The presence of the methyl group at the 1-position of the indole ring can influence its electronic properties and reactivity. This compound may exhibit various biological activities, making it of interest in pharmaceutical research. Its hydrazide moiety can participate in various chemical reactions, including hydrazone formation and potential interactions with biological targets. As with many organic compounds, safety and handling precautions should be observed, as it may pose health risks if ingested or inhaled. Overall, 1-methyl-1H-indole-3-carbohydrazide represents a versatile structure with potential applications in medicinal chemistry and related fields.

Formula: C₁₀H₁₁N₃O

InChI: InChI=1/C10H11N3O/c1-13-6-8(10(14)12-11)7-4-2-3-5-9(7)13/h2-6H,11H2,1H3,(H,12,14)

SMILES: Cn1cc(c2ccccc12)C(=NN)O

Synonyms:

• 1H-Indole-3-carboxylic acid, 1-methyl-, hydrazide

1-Methyl-1H-indole-3-carbohydrazide

Controlled Product

CAS: 56559-62-7

1-Methyl-1H-indole-3-carbohydrazide (MZ) is a potential anticancer drug that inhibits the growth of cancer cells. It binds to the colchicine binding site on the DNA, which prevents doxorubicin from binding and causing damage to the DNA. MZ has been shown to be effective against breast cancer and has been shown to inhibit tumor growth in mice by targeting cancer cells lines. MZ also inhibits proliferation of MDA-MB-231 cells in culture, as well as inhibiting cell cycle progression, leading to apoptosis. The molecular docking studies show that 1MZ binds to colchicine site on DNA with high affinity and specificity.

Formula: C₁₀H₁₁N₃O

Purity: Min. 95%

Molecular weight: 189.21 g/mol

Ref: 3D-FM114293