CAS 566-03-0

Tetrahydro-11-dehydrocorticosterone

Description:

Tetrahydro-11-dehydrocorticosterone (THDOC) is a steroid hormone that is a derivative of corticosterone, primarily involved in the regulation of various physiological processes, including stress response and metabolism. It is characterized by its four-ring steroid structure, which is typical of corticosteroids, and features a reduced double bond at the 11-position, contributing to its biological activity. THDOC is known to exhibit mineralocorticoid and glucocorticoid properties, influencing electrolyte balance and immune response. It is synthesized in the adrenal cortex and can be found in various tissues, playing a role in the modulation of neuronal activity and behavior. The substance is also studied for its potential effects on the central nervous system, particularly in relation to anxiety and mood disorders. As a chemical entity, THDOC is identified by its CAS number 566-03-0, which serves as a unique identifier for regulatory and research purposes. Its solubility and stability can vary depending on the conditions, making it important for researchers to consider these factors in experimental applications.

Formula: C₂₁H₃₂O₄

InChI: InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13-,14+,15+,16-,19-,20+,21+/m1/s1

InChI key: InChIKey=XWYBFXIUISNTQG-RHBMFIQRSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3=O)[C@@H](C(CO)=O)CC4)[H])(CC[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Synonyms:

• (3Alpha)-3,21-Dihydroxypregnane-11,20-Dione
• (3Alpha,5Beta)-3,21-Dihydroxypregnane-11,20-Dione
• (3α,5β)-3,21-Dihydroxypregnane-11,20-dione
• 11-Dehydrotetrahydrocorticosterone
• 3,21-Dihydroxypregnane-11,20-Dione
• 3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione
• 3α,21-Dihydroxy-5β-pregnane-11,20-dione
• 5β-Pregnane-11,20-dione, 3α,21-dihydroxy-
• 5β-Pregnane-3α,21-diol-11,20-dione
• NSC 11574
• Pregnane-11,20-dione, 3,21-dihydroxy-, (3α,5β)-
• Tetrahydro Kendall's compound A
• Tetrahydro-11-dehydrocorticosterone

Tetrahydro-11-dehydrocorticosterone

CAS: 566-03-0

Tetrahydro-11-dehydrocorticosterone

Purity: 98%

Molecular weight: 348.48g/mol

Ref: 54-OR1075562

Tetrahydrodehydrocorticosterone

CAS: 566-03-0

Formula: C₂₁H₃₂O₄

Molecular weight: 348.48

Ref: 4Z-C-10413

Tetrahydrodehydrocor​ticosterone

Controlled Product

CAS: 566-03-0

Applications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.
References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)

Formula: C₂₁H₃₂O₄

Color and Shape: Neat

Molecular weight: 348.48

Ref: TR-T293165

5β-Pregnan-3α,21-diol-11,20-dione

Controlled Product

CAS: 566-03-0

5beta-Pregnan-3alpha,21-diol-11,20-dione (5beta-pregnan) is a fine chemical used in research and development as a building block or intermediate. It has many uses, including as a useful scaffold for complex compounds. This chemical is also an excellent reagent for the synthesis of new organic compounds. It is a versatile building block that can be used in the production of high quality speciality chemicals. 5beta-pregnan may be used to synthesize many different types of building blocks and intermediates that are useful for the synthesis of other compounds.

Formula: C₂₁H₃₂O₄

Purity: (Tlc) Min. 95.0%

Color and Shape: Powder

Molecular weight: 348.48 g/mol

Ref: 3D-FP65906

Tetrahydro-11-dehydrocorticosterone

CAS: 566-03-0

Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].

Formula: C₂₁H₃₂O₄

Color and Shape: Solid

Molecular weight: 348.48

Ref: TM-T81010