CAS 566-27-8
:7β-Hydroxycholesterol
Description:
7β-Hydroxycholesterol is a sterol compound that plays a significant role in cholesterol metabolism and is a precursor in the biosynthesis of various steroid hormones. It is characterized by the presence of a hydroxyl group at the 7β position of the cholesterol molecule, which influences its biological activity and solubility. This compound is typically found in biological membranes and is involved in cellular signaling pathways. It can also serve as a marker for certain physiological and pathological conditions, particularly in the context of cardiovascular diseases and neurodegenerative disorders. 7β-Hydroxycholesterol is known to exhibit both pro-inflammatory and cytotoxic effects, which can impact cell viability and function. Its presence in the body can be indicative of altered cholesterol metabolism, and it is often studied in the context of atherosclerosis and other lipid-related disorders. As a chemical entity, it has a specific molecular structure that contributes to its reactivity and interactions with other biomolecules.
Formula:C27H46O2
InChI:InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1
InChI key:InChIKey=OYXZMSRRJOYLLO-KGZHIOMZSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=C[C@@H]3O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Synonyms:- (3β,7β)-Cholest-5-ene-3,7-diol
- Δ5-Cholestene-3β,7β-diol
- 7β-Hydroxycholesterol
- Cholest-5-ene-3β,7β-diol
- Cholest-5-ene-3,7-diol, (3β,7β)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.
7 β-Hydroxycholesterol
CAS:<p>7 Beta-Hydroxycholesterol (7β-Hydroxycholesterol) is an oxidative stress inducer that promotes atherosclerosis.</p>Formula:C27H46O2Purity:99.24%Color and Shape:SolidMolecular weight:402.657-β-Hydroxycholesterol
CAS:Formula:C27H46O2Purity:(TLC) ≥ 95.0%Color and Shape:White powderMolecular weight:402.657b-Hydroxy Cholesterol-d7
CAS:Controlled ProductFormula:C27H39D7O2Color and Shape:NeatMolecular weight:409.77β-Hydroxy Cholesterol
CAS:Controlled Product<p>Applications A metabolite of Cholesterol. Its membrane organizing properties could have implications in Altzheimer’s disease.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007); S.L. Regen et al.: J. Amer. Chem. Soc., 131, 12354 (2009)<br></p>Formula:C27H46O2Color and Shape:NeatMolecular weight:402.657b-Hydroxy cholesterol
CAS:Controlled Product<p>7b-Hydroxycholesterol is a cholesterol metabolite that is formed from 7-alpha-hydroxylase by cytochrome P450. It has been shown to induce apoptosis in a number of carcinoma cell lines, including HL-60 cells and human prostate cancer cells. 7b-hydroxycholesterol was also shown to be an effective inducer of the formation of body structures by cultured cells. It has been found to be potent inducers of the synthesis of oxysterols, which are natural compounds that have been shown to inhibit viral replication. The effects on body formation and viral inhibition may be due to its ability to bind to the mitochondrial membrane potential, inhibiting ATP binding cassette transporter and enzyme activities.</p>Formula:C27H46O2Purity:Min. 95%Color and Shape:PowderMolecular weight:402.65 g/mol
