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CAS 566-35-8

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Pregn-4-ene-3,20-dione,11,17,21-trihydroxy-, (11a)-

Description:
Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11a)-, commonly known as hydrocortisone or cortisol, is a steroid hormone produced by the adrenal cortex. It plays a crucial role in various physiological processes, including metabolism regulation, immune response modulation, and stress response. This compound has a molecular formula that reflects its steroid structure, featuring four fused carbon rings. Hydrocortisone is characterized by the presence of hydroxyl (-OH) groups at positions 11, 17, and 21, which contribute to its biological activity. It exhibits anti-inflammatory and immunosuppressive properties, making it a key therapeutic agent in treating conditions such as allergies, asthma, and autoimmune disorders. Additionally, hydrocortisone is involved in glucose metabolism and helps maintain blood pressure. Its pharmacological effects are mediated through binding to glucocorticoid receptors, influencing gene expression and cellular function. Due to its significant role in the body, hydrocortisone is also used in various formulations for topical and systemic administration in clinical settings.
Formula:C21H30O5
Synonyms:
  • Pregn-4-ene-3,20-dione,11a,17,21-trihydroxy- (8CI)
  • 11-Epicortisol
  • 11-Epihydrocortisone
  • 11-Isocortisol
  • 11a,17,21-Trihydroxypregn-4-ene-3,20-dione
  • 11a,17,21-Trihydroxypregnen-4-en-3,20-dione
  • 11a,17a,21-Trihydroxy-4-pregnene-3,20-dione
  • 11a,17a,21-Trihydroxyprogesterone
  • 11a-Cortisol
  • 11a-Epicortisol
  • See more synonyms
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