CAS 566-63-2

(3beta,17alpha)-3-hydroxypregn-5-en-20-one

Description:

The chemical substance known as (3beta,17alpha)-3-hydroxypregn-5-en-20-one, with the CAS number 566-63-2, is commonly referred to as progesterone. It is a steroid hormone that plays a crucial role in the menstrual cycle, pregnancy, and embryogenesis in humans and other species. Progesterone is synthesized from cholesterol and is primarily produced in the ovaries, placenta, and adrenal glands. Its molecular structure features a steroid backbone with a hydroxyl group at the 3-position and a double bond between the 5 and 6 positions, contributing to its biological activity. Progesterone is lipophilic, allowing it to easily cross cell membranes and bind to specific nuclear receptors, influencing gene expression. It is involved in regulating various physiological processes, including the preparation of the endometrium for potential implantation of an embryo and maintaining pregnancy. Additionally, progesterone has therapeutic applications in hormone replacement therapy and in the treatment of certain reproductive disorders.

Formula: C₂₁H₃₂O₂

InChI: InChI=1/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19,23H,5-12H2,1-3H3/t15-,16-,17-,18-,19-,20-,21+/m0/s1

Synonyms:

• 17.alpha.-Pregn-5-en-20-one, 3.beta.-hydroxy-
• Pregn-5-en-20-one, 3-hydroxy-, (3.beta.,17.alpha.)-

Progesterone Impurity 33

CAS: 566-63-2

Formula: C₂₁H₃₂O₂

Molecular weight: 316.49

Ref: 4Z-P-32109

17-epi-Pregnenolone

Controlled Product

CAS: 566-63-2

Applications 17-epi-Pregnenolone is an impurity of Pregnenolone(P712200). Pregnenolone is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.
References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),

Formula: C₂₁H₃₂O₂

Color and Shape: Neat

Molecular weight: 316.48

Ref: TR-P566630

Pregnenolon

Controlled Product

CAS: 566-63-2

Pregnenolon is a corticosteroid hormone with anti-inflammatory, antiseptic and antipyretic properties. It is used in the treatment of adrenocortical carcinoma, which is a type of cancer that develops in the gland that produces hormones such as cortisol and aldosterone. Pregnenolon can be administered intravenously or orally, however it has to be injected intramuscularly for use against hypertrophy in animals. This hormone is also used to diagnose diseases of the testes, ovaries, and other tissues. Pregnenolon binds to receptors on cells called glucocorticoid receptors, which are found in most tissues of the body. When these receptors are activated by pregnenolon they inhibit protein synthesis and cause rapid breakdown of fats and proteins. This leads to an accumulation of fat droplets in cells (lipidosis) and a decrease in cellular function. Pregnenolon also has an active form known as pregnenol

Formula: C₂₁H₃₂O₂

Purity: Min. 95%

Molecular weight: 316.48 g/mol

Ref: 3D-FP178381

Progesterone Impurity 33

CAS: 566-63-2

Formula: C₂₁H₃₂O₂

Molecular weight: 316.49

Ref: ST-EA-CP-P133144