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CAS 56632-83-8

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4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone

Description:
4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone, with the CAS number 56632-83-8, is a nucleoside analog that exhibits structural similarities to naturally occurring nucleosides. This compound features a pyrimidinone base linked to a deoxyribose sugar, specifically a 2-deoxy-2-fluoro modification, which enhances its stability and bioactivity. The presence of an amino group at the 4-position of the pyrimidine ring contributes to its potential as an antiviral or anticancer agent, as it may interfere with nucleic acid synthesis. The fluorine substitution on the sugar moiety can influence the compound's pharmacokinetics and binding affinity to target enzymes or receptors. This substance is of interest in medicinal chemistry and pharmaceutical research, particularly in the development of therapeutics aimed at viral infections or malignancies. Its unique structural features may also allow for further modifications to optimize efficacy and reduce toxicity in clinical applications.
Formula:C9H12FN3O4
InChI:InChI=1/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6+,7-,8-/m1/s1
Synonyms:
  • 4-Amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
  • 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine
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