CAS 567-03-3

Tetrahydrodeoxycorticosterone

Description:

Tetrahydrodeoxycorticosterone (THDOC) is a steroid hormone that belongs to the class of corticosteroids. It is a metabolite of deoxycorticosterone and is primarily produced in the adrenal glands. THDOC plays a role in the regulation of electrolyte balance and has been implicated in various physiological processes, including the modulation of blood pressure and stress response. The substance is characterized by its four-ring steroid structure, which is typical of corticosteroids, and it exhibits both mineralocorticoid and glucocorticoid activity, albeit to a lesser extent than other corticosteroids like cortisol. THDOC is known to interact with mineralocorticoid receptors, influencing sodium and potassium balance in the body. Additionally, it has been studied for its potential neuroactive properties, as it can cross the blood-brain barrier and may affect mood and behavior. Due to its hormonal nature, THDOC is subject to regulation in various contexts, particularly in sports and medicine, where its use may be monitored for performance enhancement or therapeutic purposes.

Formula:C₂₁H₃₄O₃

InChI:InChI=1S/C21H34O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13-18,22-23H,3-12H2,1-2H3/t13-,14-,15+,16+,17+,18-,20+,21+/m1/s1

InChI key:InChIKey=CYKYBWRSLLXBOW-DATPGIFZSA-N

SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@H]2C(CO)=O)[H]

Synonyms:

(3Alpha,5Alpha)-3,21-Dihydroxypregnan-20-One
(3Alpha,5Beta)-3,21-Dihydroxypregnan-20-One
(3α,5β)-3,21-Dihydroxypregnan-20-one
21-Hydroxypregnanolone
3alpha,21-Dihydroxy-5beta-pregnan-20-one
3α,21-Dihydroxy-5β-pregnan-20-one
3α,5β-Tetrahydrodeoxycorticosterone
5β-Pregnan-20-one, 3α,21-dihydroxy-
5β-Pregnan-3α,21-diol-20-one
Corticosterone, 11-deoxytetrahydro-
Corticosterone, deoxytetrahydro-
Deoxytetrahydrocorticosterone
Pregnan-20-one, 3,21-dihydroxy-, (3α,5β)-
Tetrahydro DOC
Tetrahydro-11-deoxycorticosterone
See more synonyms

Purity (%)

100

Found 9 products.

+ Info
Tetrahydrodeoxycorticosterone
CAS:
- 567-03-3
Tetrahydrodeoxycorticosterone
Formula:C₂₁H₃₄O₃
Purity:98%
Molecular weight:334.49
Ref: 54-OR1137980
1mg
832.00€
VAT not included
5mg
1,878.00€
VAT not included
+ Info
Tetrahydrodeoxycorticosterone
CAS:
- 567-03-3
Purity:98%
Ref: IN-DA00EBWF
1mg
628.00€
VAT not included
5mg
1,568.00€
VAT not included
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5β-Pregnan-3α,21-diol-20-one-17α,21,21-d3
CAS:
- 567-03-3
- 72205-58-4
Purity:97 atom % D
Color and Shape:White Solid
Molecular weight:337.52
Ref: 3U-D6461
5mg
1,203.00€
VAT not included
10mg
1,987.00€
VAT not included
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Tetrahydrodeoxycorticosterone
CAS:
- 567-03-3
Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-induced currents at the GABAA receptor, and can be used in the study of neurological disorders.
Formula:C₂₁H₃₄O₃
Purity:99.40%
Color and Shape:Solid
Molecular weight:334.49
Ref: TM-T37725
1mg
239.00€
VAT not included
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Tetrahydrodeoxycorticosterone (Standard)
CAS:
- 567-03-3
Tetrahydrodeoxycorticosterone (Standard) is a reference standard for research and analysis in studies involving Tetrahydrodeoxycorticosterone. Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-induced currents at the GABAA receptor, and can be used in the study of neurological disorders.
Formula:C₂₁H₃₄O₃
Color and Shape:Solid
Molecular weight:334.49
Ref: TM-TMSM-3253
1mg
290.00€
VAT not included
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Tetrahydro 11-Deoxycorticosterone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 567-03-3
Applications Tetrahydro 11-Deoxycorticosterone is a metabolite of 11-Deoxycorticosterone (DOC) (D232590).
References Fedele, E., et al.: J. Neurochem., 75, 782 (2000), Adkins, C., et al.: J. Biol. Chem., 276, 38934 (2001), Erceg, S., et al.: Brain Res., 1036, 115 (2005),
Formula:C₂₁H₃₄O₃
Color and Shape:Neat
Molecular weight:334.49
Ref: TR-T293270
5mg
255.00€
VAT not included
10mg
353.00€
VAT not included
50mg
1,353.00€
VAT not included
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Tetrahydro 11-deoxycorticosterone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 567-03-3
Tetrahydro 11-deoxycorticosterone is a model system that is used to study the effects of steroids on the nervous system. It has been shown to bind to the α1 subunit of receptors and can also block cation channels. Tetrahydro 11-deoxycorticosterone may be useful in treating diseases such as Alzheimer's disease, epilepsy, and schizophrenia. This drug has also been shown to have a positive effect on body mass index in women.
Formula:C₂₁H₃₄O₃
Purity:Min. 95%
Color and Shape:Powder
Molecular weight:334.49 g/mol
Ref: 3D-FT28081
2mg
247.00€
VAT not included
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21-Hydroxypregnanolone
CAS:
- 567-03-3
Ref: BE-MU-2230
1mg
186.00€
VAT not included
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Tetrahydro 11-Deoxycorticosterone-D5
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 567-03-3
Formula:C₂₁D₅H₂₉O₃
Color and Shape:Neat
Molecular weight:339.524
Ref: TR-T293272
25mg
5,142.00€
VAT not included