CAS 56776-32-0

Etifoxine hydrochloride

Description:

Etifoxine hydrochloride is a chemical compound primarily recognized for its anxiolytic properties, often used in the treatment of anxiety disorders. It functions as a modulator of the GABAergic system, enhancing the effects of gamma-aminobutyric acid (GABA), a key neurotransmitter that promotes relaxation and reduces neuronal excitability. The substance is characterized by its relatively low toxicity and a favorable side effect profile compared to traditional anxiolytics, making it a preferred option in certain therapeutic contexts. Etifoxine also exhibits neuroprotective effects, which may contribute to its efficacy in managing anxiety. The compound is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. Its pharmacokinetics involve rapid absorption and a moderate half-life, allowing for effective dosing regimens. As with any medication, the use of etifoxine hydrochloride should be guided by a healthcare professional, considering individual patient needs and potential interactions with other medications.

Formula: C₁₇H₁₇ClN₂O·ClH

InChI: InChI=1S/C17H17ClN2O.ClH/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2,21-16)12-7-5-4-6-8-12;/h4-11H,3H2,1-2H3,(H,19,20);1H

InChI key: InChIKey=SCBJXEBIMVRTJE-UHFFFAOYSA-N

SMILES: CC1(C=2C(N=C(NCC)O1)=CC=C(Cl)C2)C3=CC=CC=C3.Cl

Synonyms:

• 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl-, hydrochloride (1:1)
• 4H-3,1-Benzoxazin-2-amine, 6-chloro-N-ethyl-4-methyl-4-phenyl-, monohydrochloride
• 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine hydrochloride (1:1)
• Etifoxine HCl
• Etifoxine hydrochloride
• Stresam
• 6-Chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride

Etifoxine hydrochloride

CAS: 56776-32-0

Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.

Formula: C₁₇H₁₈Cl₂N₂O

Purity: 99.36%

Color and Shape: Solid

Molecular weight: 337.24

Ref: TM-T13690

6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine hydrochloride

CAS: 56776-32-0

Formula: C₁₇H₁₈Cl₂N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 337.2436

Ref: IN-DA0035VE

Etifoxine Hydrochloride

CAS: 56776-32-0

Applications Psychotropic agent with anxiolytic and anticonvulsant activity.
References Boissier, J.R., et al.: Therapie, 27, 325 (1972), Bente, D., et al.: Arzneim. Forsch., 25, 944 (1975),

Formula: C₁₇H₁₇ClN₂O·ClH

Color and Shape: Off White Solid

Molecular weight: 337.24

Ref: TR-E932750

Etifoxine hydrochloride

Controlled Product

CAS: 56776-32-0

Etifoxine hydrochloride is a drug that has been used in the treatment of asthma and other pulmonary diseases. It is a potent inhibitor of phospholipase A2, which modulates the production of inflammatory mediators. Etifoxine hydrochloride has been shown to have neurotrophic effects, with potential for clinical use in the treatment of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. This drug also has anti-inflammatory properties due to its inhibition of prostaglandin synthesis. Etifoxine hydrochloride acts as an agonist on receptors, which may be responsible for some of its biological properties, including thermal expansion and axonal growth. In addition, this drug is a competitive inhibitor of the enzyme poly(ADP-ribose) polymerase (PARP), which is involved in DNA repair and cell division.

Formula: C₁₇H₁₈Cl₂N₂O

Purity: Min. 95%

Molecular weight: 337.24 g/mol

Ref: 3D-FE23188