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CAS 5679-00-5

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7-Didemethyl Minocycline

Description:
7-Didemethyl Minocycline, identified by its CAS number 5679-00-5, is a semi-synthetic derivative of the tetracycline antibiotic minocycline. This compound exhibits antibacterial properties, primarily effective against a range of Gram-positive and Gram-negative bacteria. Its structure features modifications that enhance its pharmacological profile, including improved absorption and bioavailability compared to its parent compound. 7-Didemethyl Minocycline is known for its ability to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. Additionally, it has been studied for its anti-inflammatory properties, making it of interest in treating conditions beyond bacterial infections, such as acne and certain inflammatory diseases. The compound is typically administered orally and is characterized by its stability in various pH environments, which contributes to its effectiveness in clinical applications. As with other tetracyclines, it is important to consider potential side effects, including photosensitivity and gastrointestinal disturbances, when using this antibiotic.
Formula:C21H23N3O7
Synonyms:
  • 7-DideMethyl Minocycline Discontinued
  • Minocycline Impurity D(7-Monodemethyl Minocycline)
  • [4S-(4a,4aa,5aa,12aa)]-7-Amino-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide
  • Minocycline Impurity D (7-Aminosancycline)
  • (4S,4aS,5aR,12aS)-7-Amino-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide
  • 7-Aminosancycline
  • [4S-(4α,4aα,5aα,12aα)]-7-AMino-4-(diMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxaMide
  • 7-Aminominocycline
  • 2-Naphthacenecarboxamide, 7-amino-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
  • (4S,4aS,5aR,12aS)-7-amino-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
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