CAS 568-01-4

4,5-Dimethoxy-11-methyl-1,3-dioxolo[4,5-c]acridin-6(11H)-one

Description:

4,5-Dimethoxy-11-methyl-1,3-dioxolo[4,5-c]acridin-6(11H)-one, with CAS number 568-01-4, is a synthetic organic compound belonging to the acridine family. This compound features a complex polycyclic structure characterized by the presence of a dioxole ring and methoxy substituents, which contribute to its unique chemical properties. It typically exhibits a yellow to orange coloration and is soluble in organic solvents. The presence of methoxy groups enhances its electron-donating ability, potentially influencing its reactivity and interactions with biological systems. This compound may exhibit fluorescence, making it of interest in various applications, including photochemistry and as a potential fluorescent probe. Additionally, its structural features suggest potential biological activity, which warrants further investigation in pharmacological studies. As with many acridine derivatives, it may also be explored for its potential use in dye applications or as a precursor in organic synthesis. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₇H₁₅NO₅

InChI: InChI=1S/C17H15NO5/c1-18-10-7-5-4-6-9(10)13(19)11-12(18)15-17(23-8-22-15)16(21-3)14(11)20-2/h4-7H,8H2,1-3H3

InChI key: InChIKey=PEWWLIQAXYMMAN-UHFFFAOYSA-N

SMILES: CN1C2=C(C(OC)=C(OC)C3=C2OCO3)C(=O)C=4C1=CC=CC4

Synonyms:

• 1,3-Dioxolo(4,5-c)acridin-6(11H)-one, 4,5-dimethoxy-11-methyl- (8CI)(9CI)
• 1,3-Dioxolo[4,5-c]acridin-6(11H)-one, 4,5-dimethoxy-11-methyl-
• Melicopine
• Nsc 34758
• 4,5-Dimethoxy-11-methyl-1,3-dioxolo[4,5-c]acridin-6(11H)-one
• 4,5-Dimethoxy-11-methyl-1,3-dioxolo(4,5-c)acridin-6(11H)-one

Melicopine

CAS: 568-01-4

Melicopine is an alkaloid found in Z. simulans, known for its antimalarial and anticancer properties. It inhibits P. falciparum strains, including chloroquine-sensitive 3D7 (IC50 of 29.7 µg/mL) and chloroquine-resistant Dd2 (IC50 of 33.7 µg/mL). Additionally, Melicopine exhibits cytotoxicity against prostate cancer cells PC-3M (IC50 of 47.9 µg/mL) and LNCaP (IC50 of 37.8 µg/mL), but it is inactive in non-cancerous HEK293 cells (IC50 greater than 100 µg/mL). Melicopine holds potential for research in anticancer and anti-infective applications.

Formula: C₁₇H₁₅NO₅

Color and Shape: Solid

Molecular weight: 313.31

Ref: TM-TN8420

Melicopine

CAS: 568-01-4

Formula: C₁₇H₁₅NO₅

Purity: 95%~99%

Molecular weight: 313.309

Ref: BP-BP0932

Melicopine

CAS: 568-01-4

Melicopine is a complex alkaloid, which is derived from the plant species Melicope. This compound is extracted from natural sources, specifically found in certain plants of the Rutaceae family. The mode of action of Melicopine involves interaction with the central nervous system, potentially modulating pain signals through receptor binding and influencing neurotransmitter release.

Formula: C₁₇H₁₅NO₅

Purity: Min. 95%

Molecular weight: 313.3 g/mol

Ref: 3D-FM65855