CAS 5689-59-8

N-1-Adamantyl-2-chloroacetamide

Description:

N-1-Adamantyl-2-chloroacetamide is a chemical compound characterized by its adamantyl group, which is a bicyclic structure known for its rigidity and stability. This compound features a chloroacetamide functional group, which contributes to its reactivity and potential biological activity. Typically, it appears as a solid at room temperature and is soluble in organic solvents. The presence of the chlorine atom in the chloroacetamide moiety can influence its chemical properties, such as polarity and reactivity, making it a subject of interest in medicinal chemistry. The adamantyl group is often associated with enhanced lipophilicity, which can affect the compound's pharmacokinetics and interaction with biological targets. N-1-Adamantyl-2-chloroacetamide may exhibit various biological activities, including potential antiviral or anticancer properties, making it a candidate for further research in drug development. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity or reactivity.

Formula: C₁₂H₁₈ClNO

InChI: InChI=1S/C12H18ClNO/c13-7-11(15)14-12-4-8-1-9(5-12)3-10(2-8)6-12/h8-10H,1-7H2,(H,14,15)

InChI key: InChIKey=PJRVXDKETNCCKR-UHFFFAOYSA-N

SMILES: N(C(CCl)=O)C12CC3CC(C1)CC(C2)C3

Synonyms:

• 1-Chloroacetylaminoadamantane
• 2-Chloro-N-tricyclo[3.3.1.1^3,7]dec-1-ylacetamide
• Acetamide, 2-chloro-N-tricyclo[3.3.1.1^3,7]dec-1-yl-
• Acetamide, 2-chloro-N-tricyclo[3.3.1.1~3,7~]dec-1-yl-
• Acetamide, N-1-adamantyl-2-chloro-
• N-(Adamantan-1-yl)-2-chloroacetamide
• N-1-Adamantyl-2-chloroacetamide
• N-Adamantan-1-Yl-2-Chloro-Acetamide
• N-Chloroacetyl-1-aminoadamantane
• Acetamide, 2-chloro-N-tricyclo[3.3.1.13,7]dec-1-yl-
• 2-Chloro-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide

N-Adamantan-1-yl-2-chloro-acetamide

CAS: 5689-59-8

Formula: C₁₂H₁₈ClNO

Color and Shape: Solid

Molecular weight: 227.7304

Ref: IN-DA00EAC2

1-(Chloroacetylamino) Adamantane (CAAA)

CAS: 5689-59-8

Formula: C₁₂H₁₈ClNO

Color and Shape: Off-White Solid

Molecular weight: 227.73

Ref: 4Z-A-124003

N-1-Adamantyl-2-chloroacetamide

CAS: 5689-59-8

Adamantyl-2-chloroacetamide is an analog of adamantyl acetamide and has been shown to be a potent inhibitor of Mycobacterium tuberculosis. Adamantyl-2-chloroacetamide inhibits the growth of Mycobacterium tuberculosis by inhibiting the synthesis of DNA, RNA, and protein. This compound also shows selectivity for Mycobacterium tuberculosis over other bacteria such as Escherichia coli. Adamantyl-2-chloroacetamide may have a role in the treatment of tuberculosis because it can inhibit the synthesis of DNA, RNA, and protein in Mycobacterium tuberculosis while leaving these functions intact in other bacteria.

Formula: C₁₂H₁₈ClNO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 227.73 g/mol

Ref: 3D-FA114099

1-(Chloroacetylamino) Adamantane

CAS: 5689-59-8

Formula: C₁₂H₁₈ClNO

Molecular weight: 227.73

Ref: ST-EA-CP-A73007