CAS 569660-89-5

(S)-3-Bromo-pyrrolidine-1-carboxylic acid tert-butyl ester

Description:

(S)-3-Bromo-pyrrolidine-1-carboxylic acid tert-butyl ester is a chiral compound characterized by its pyrrolidine ring structure, which is a five-membered cyclic amine. The presence of a bromine atom at the 3-position introduces a halogen substituent, influencing the compound's reactivity and potential applications in organic synthesis. The tert-butyl ester group enhances the lipophilicity of the molecule, making it more soluble in organic solvents while also providing a protective group for the carboxylic acid functionality. This compound is typically used in the synthesis of various pharmaceuticals and biologically active molecules due to its ability to serve as a building block in asymmetric synthesis. Its chirality is significant in medicinal chemistry, as the specific enantiomer may exhibit different biological activities. Additionally, the compound's stability and reactivity can be influenced by the presence of the bromine atom and the tert-butyl ester, making it a versatile intermediate in chemical reactions. Overall, (S)-3-Bromo-pyrrolidine-1-carboxylic acid tert-butyl ester is an important compound in the field of synthetic organic chemistry.

Formula: C₉H₁₆NO₂Br

InChI: InChI=1S/C9H16BrNO2/c1-9(2,3)13-8(12)11-5-4-7(10)6-11/h7H,4-6H2,1-3H3/t7-/m0/s1

SMILES: CC(C)(C)OC(=O)N1CC[C@@H](C1)Br

Synonyms:

• (S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate
• 1-Pyrrolidinecarboxylic acid, 3-bromo-, 1,1-dimethylethyl ester, (3S)-

(S)-(+)-1-Boc-3-bromopyrrolidine, 95%

CAS: 569660-89-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₁₆BrNO₂

Purity: 95%

Molecular weight: 250.14

Ref: 02-H57408

(S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate

CAS: 569660-89-5

Formula: C₉H₁₆BrNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 250.1328

Ref: IN-DA00ED6K

[S]-1-Boc-3-Bromopyrrolidine

CAS: 569660-89-5

[S]-1-Boc-3-Bromopyrrolidine

Purity: 95%

Color and Shape: Off-White Solid

Molecular weight: 250.13g/mol

Ref: 54-OR309144

(S)-3-Bromo-pyrrolidine-1-carboxylic acid tert-butyl ester

CAS: 569660-89-5

Formula: C₉H₁₆BrNO₂

Purity: 98%

Molecular weight: 250.136

Ref: 10-F088273

(S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate

CAS: 569660-89-5

(S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate is a reagent that can be used for the synthesis of chiral compounds. It reacts with chlorosulfonyl isocyanate to form an N-substituted sulfonamide. This reaction proceeds with high stereoselectivity, yielding the desired product in high yield and enantiomeric excess. (S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate can also be used as a desulfonylation reagent and has been shown to react with c1–c6 alkoxy groups to form alcohols. (S)-tert-Butyl 3-bromopyrrolidine-1-carboxylate reacts with nitro groups to form nitroso derivatives, octane to produce cyclohexanones, benzyl group to make phenols, piperidine to

Formula: C₉H₁₆BrNO₂

Purity: Min. 95%

Molecular weight: 250.13 g/mol

Ref: 3D-UXA66089