CAS 57-29-4

Nalorphine hydrochloride

Description:

Nalorphine hydrochloride is a synthetic opioid derivative primarily known for its role as a partial agonist and antagonist at opioid receptors. It is characterized by its ability to reverse the effects of opioid overdose while still providing some analgesic properties, making it a unique compound in pain management and addiction treatment. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration via injection. Nalorphine acts primarily on the mu-opioid receptors, where it exhibits a lower affinity compared to full agonists, thus mitigating the euphoric effects associated with stronger opioids. Its pharmacological profile includes respiratory depression reversal, which is crucial in overdose situations. However, due to its mixed agonist-antagonist properties, nalorphine is less commonly used today, having been largely replaced by more effective and safer alternatives. As with all opioids, nalorphine hydrochloride must be used with caution due to the potential for dependence and withdrawal symptoms.

Formula:C₁₉H₂₁NO₃·ClH

InChI:InChI=1S/C19H21NO3.ClH/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20;/h2-6,12-13,15,18,21-22H,1,7-10H2;1H/t12-,13+,15-,18-,19-;/m0./s1

InChI key:InChIKey=NAHATSPWSULUAA-ZQGPYOJVSA-N

SMILES:O[C@@H]1[C@]2([C@]34C=5C(O2)=C(O)C=CC5C[C@]([C@@]3(C=C1)[H])(N(CC=C)CC4)[H])[H].Cl

Synonyms:

(5Alpha,6Alpha)-17-Prop-2-En-1-Yl-7,8-Didehydro-4,5-Epoxymorphinan-3,6-Diol Hydrochloride
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α,6α)-
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, hydrochloride, (5α,6α)-
Morphinan-3,6α-diol, 17-allyl-7,8-didehydro-4,5α-epoxy-, hydrochloride
N-Allylnormorphine hydrochloride
Naline hydrochloride
Nalorphine Hydrochloride
Nalorphine chloride
Nih 10124

The purity filter is not visible because current products do not have associated purity data for filtering.

Found 10 products.

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Nalorphine Hydrochloride 1.0 mg/ml in Methanol (as free base)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Color and Shape:Single Solution
Ref: 61-AMP1013.00-01
1ml
92.00€
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Nalorphine.HCl, 1mg/ml in Methanol (as free base)
CAS:
- 57-29-4
Color and Shape:Single Solution
Ref: LP-M-777-HC-1LM
1ml
51.00€
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Nalorphine.HCl
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Color and Shape:Neat
Ref: LP-M-777-HC-10
10mg
207.00€
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50mg
668.00€
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100mg
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Nalorphine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Color and Shape:Neat
Ref: 61-FOR1013.00
10mg
360.00€
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Nalorphine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Formula:C₁₉H₂₁NO₃·ClH
Color and Shape:Neat
Molecular weight:347.836
Ref: 86-MM1013.00
100mg
397.00€
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Nalorphine Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Applications Narcotic antagonist.Controlled substance. References McCawley, H., et al.: J. Pharmacol., 82, 339 (1944), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Zubair, M.U., et al.: Anal. Profiles Drug Subs., 18, 195 (1989), 
Formula:C₁₉H₂₁NO₃·ClH
Color and Shape:Neat
Molecular weight:347.836
Ref: TR-N284450
25mg
96.00€
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50mg
162.00€
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Nalorphine Hydrochloride (1 mg/ml in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Formula:C₁₉H₂₁NO₃·ClH
Color and Shape:Single Solution
Molecular weight:347.836
Ref: TR-KIT6360
5x1ml
946.00€
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Nalorphine-d5 Hydrochloride (1 mg/ml in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Formula:C₁₉H₁₇D₅ClNO₃
Color and Shape:Single Solution
Molecular weight:352.87
Ref: TR-KIT6365
1x1ml
432.00€
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Nalorphine-d5 Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Applications Narcotic antagonist.Controlled substance. References McCawley, H., et al.: J. Pharmacol., 82, 339 (1944), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Zubair, M.U., et al.: Anal. Profiles Drug Subs., 18, 195 (1989), 
Formula:C₁₉H₁₇D₅ClNO₃
Color and Shape:Neat
Molecular weight:352.87
Ref: TR-N284452
1mg
236.00€
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10mg
1,572.00€
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Nalorphine Hydrochloride CIII
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-29-4
Alkaloids of opium and their derivatives, salts thereof
Formula:C₁₉H₂₁NO₃·ClH
Color and Shape:Powder
Molecular weight:347.12882
Ref: 45-1452002