CAS 57-33-0

Pentobarbital sodium

Description:

Pentobarbital sodium is a barbiturate, primarily used as a sedative and anesthetic in medical settings. It appears as a white to off-white crystalline powder and is highly soluble in water, which facilitates its administration via injection. The substance acts as a central nervous system depressant, enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to sedation, hypnosis, and muscle relaxation. Pentobarbital sodium is often utilized in veterinary medicine and for euthanasia in animals, as well as in certain medical procedures requiring sedation. Due to its potential for abuse and dependence, it is classified as a controlled substance in many jurisdictions. Side effects may include drowsiness, dizziness, and respiratory depression, particularly at higher doses or when combined with other depressants. Careful monitoring is essential when administering this drug to avoid complications. As with all barbiturates, the risk of overdose is significant, necessitating strict adherence to dosing guidelines.

Formula: C₁₁H₁₈N₂O₃·Na

InChI: InChI=1S/C11H18N2O3.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);

InChI key: InChIKey=UAMVYWFSQGYHFV-UHFFFAOYSA-N

SMILES: C(CCC)(C)C1(CC)C(=O)NC(=O)NC1=O.[Na]

Synonyms:

• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-, sodium salt (1:1)
• 5-Ethyl-5-(1-methylbutyl) barbituric acid sodium salt
• 5-Ethyl-5-(methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione monosodium salt
• 844
• Auropan
• Barbituric acid, 5-ethyl-5-(1-methylbutyl)-, sodium salt
• Barpental
• Biosedan
• Butylone
• Diabutal
• Embutal
• Entobar
• Etaminal sodium
• Ethaminal sodium
• Euthanyl
• Euthatal
• Isobarb
• Mebubarbital sodium
• Mebumal sodium
• Mebunat
• Napental
• Narcoren
• Nembutal sodium
• Nsc 10816
• Pacifan
• Pental
• Pentobarbital Sodico
• Pentobarbital Sodium
• Pentobarbital sodique
• Pentobarbitalnatrium
• Pentobarbitone sodium
• Pentonal
• Pentone
• Praecicalm
• RS-Pentobarbital sodium
• Sagatal
• Sodium 5-ethyl-5-(1-methylbutyl)barbiturate
• Sodium ethaminal
• Sodium nembutal
• Sodium pental
• Sodium pentobarbital
• Sodium pentobarbitone
• Sodium pentobarbiturate
• Sodium-Pent
• Soluble pentobarbital
• Somnopentyl
• Somnotol
• Sopental
• Sotyl
• V-Pento
• Vetbutal

Pentobarbital.sodium salt, 1mg/ml in Methanol (as free Acid)

Controlled Product

CAS: 57-33-0

Color and Shape: Single Solution

Ref: LP-PTB-537-NA-1LM

Pentobarbital.sodium salt

Controlled Product

CAS: 57-33-0

Color and Shape: Neat

Ref: LP-PTB-537-NA-10

Pentobarbital Sodium

Controlled Product

CAS: 57-33-0

Formula: C₁₁H₁₇N₂O₃·Na

Color and Shape: Neat

Molecular weight: 248.25

Ref: 86-MM1368.00

Pentobarbital-d5 Sodium Salt

Controlled Product

CAS: 57-33-0

Applications Pentobarbital-d5 Sodium Salt is the labelled derivative of Pentobarbital (P276000), a narcotic and sedative barbiturate drug formerly used to relieve insomnia.
References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Woster, P.S., et al.: Clin. Pharm., 9, 762 (1990), Evans, A.T., et al.: J. Am. Vet. Med. Assoc., 203, 664 (1993),

Formula: C₁₁D₅H₁₂N₂NaO₃

Color and Shape: Neat

Molecular weight: 253.285

Ref: TR-P276002

Pentobarbital Sodium Salt (>90%)

Controlled Product

CAS: 57-33-0

Formula: C₁₁H₁₇N₂O₃·Na

Purity: >90%

Color and Shape: White

Molecular weight: 248.25

Ref: TR-P276000

PENTOBARBITAL SODIUM CRS - * PSY

Controlled Product

CAS: 57-33-0

PENTOBARBITAL SODIUM CRS - * PSY

Color and Shape: Added Added

Ref: 41-Y0002194

Pentobarbital Sodium Salt (1.0 mg/mL in Methanol)

Controlled Product

CAS: 57-33-0

Formula: C₁₁H₁₇N₂O₃·Na

Color and Shape: Single Solution

Molecular weight: 248.25

Ref: TR-KIT1330