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CAS 57-42-1

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Meperidine

Description:
Meperidine, also known as pethidine, is a synthetic opioid analgesic primarily used for the relief of moderate to severe pain. It is classified as a Schedule II controlled substance due to its potential for abuse and dependence. The chemical formula of meperidine is C15H21NO2, and it features a phenylpiperidine structure, which contributes to its analgesic properties. Meperidine acts primarily as a mu-opioid receptor agonist, providing pain relief by altering the perception of pain in the brain. It has a relatively rapid onset of action, making it suitable for acute pain management, particularly in surgical settings. However, its use is limited by side effects, including nausea, dizziness, and respiratory depression, as well as the risk of accumulation and toxicity, especially in patients with renal impairment. Due to these concerns, meperidine is often replaced by other opioids with a better safety profile in clinical practice. It is important to use meperidine under strict medical supervision to mitigate risks associated with its use.
Formula:C15H21NO2
InChI:InChI=1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3
InChI key:InChIKey=XADCESSVHJOZHK-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C1(CCN(C)CC1)C2=CC=CC=C2
Synonyms:
  • 1-Methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester
  • 4-Carbethoxy-1-methyl-4-phenylpiperidine
  • Demerol
  • Ethyl 1-methyl-4-phenylisonipecotate
  • Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
  • Ethyl-(1-Methyl-4-Phenyl-4-Piperidinecarboxylate)
  • Isonipecaine
  • Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester
  • Meperidine
  • Meperidol
  • See more synonyms
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