CAS 57-44-3

Barbital

Description:

Barbital, with the CAS number 57-44-3, is a barbiturate that was historically used as a sedative and hypnotic agent. It is a white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Chemically, barbital is classified as a 5-ethyl-5-isobutylbarbituric acid derivative, which contributes to its pharmacological properties. The substance acts primarily as a central nervous system depressant, enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to sedation and anxiolytic effects. While barbital was once widely prescribed, its use has declined due to the development of safer alternatives and concerns regarding dependence and overdose. It is important to note that barbital is a controlled substance in many jurisdictions, reflecting its potential for abuse and the need for careful regulation in medical contexts.

Formula:C₈H₁₂N₂O₃

InChI:InChI=1S/C8H12N2O3/c1-3-8(4-2)5(11)9-7(13)10-6(8)12/h3-4H2,1-2H3,(H2,9,10,11,12,13)

InChI key:InChIKey=FTOAOBMCPZCFFF-UHFFFAOYSA-N

SMILES:C(C)C1(CC)C(=O)NC(=O)NC1=O

Synonyms:

5,5-DiEthylpyrimidine-2,4,6-trione
5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
5,5-Diethylbarbituric acid
5,5-Diethylhexahydropyrimidine-2,4,6-trione
Barbital
Barbitone
Barbiturate Acid, Diethyl-
Barbituric acid, 5,5-diethyl-
Deba
Diemal
Diethylbarbitone
Diethylbarbituric acid
Diethylmalonylurea
Dormonal
Ethylbarbital
Hypnogene
Malonal
Nsc 31352
Sedeval
Uronal
Veroletten
Veronal
Veronal acetate
Vesperal
See more synonyms

Purity (%)

100

Found 9 products.

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Barbital
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Formula:C₈H₁₂N₂O₃
Color and Shape:Neat
Molecular weight:184.19
Ref: 86-MM1721.00
100mg
468.00€
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Barbital, 1mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Color and Shape:Single Solution
Ref: LP-BRB-401-FA-1LM
1ml
51.00€
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Barbital
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Color and Shape:Neat
Ref: LP-BRB-401-FA-10
10mg
93.00€
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50mg
204.00€
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100mg
333.00€
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Barbital
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Color and Shape:Neat
Ref: 61-FOR1721.00
50mg
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100mg
To inquire
10mg
93.00€
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Barbital 1.0 mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Color and Shape:Single Solution
Ref: 61-AMP1721.00-01
1ml
188.00€
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Barbital 0.1 mg/ml in Methanol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Color and Shape:Single Solution
Ref: 61-AMP1721.00-02
1ml
119.00€
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Barbital
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Applications Prototype of the barbiturate hypnotics.
References Kholod, Y., et al.: Environ. Sci. Technol., 43, 9208 (2009), Yu, J., et al.: Pharm. Res., 27, 457 (2010), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),
Formula:C₈H₁₂N₂O₃
Color and Shape:Neat
Molecular weight:184.19
Ref: TR-B118500
500mg
182.00€
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5g
1,361.00€
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Barbital (1 mg/ml in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Formula:C₈H₁₂N₂O₃
Color and Shape:Single Solution
Molecular weight:184.19
Ref: TR-KIT3105
5x1ml
404.00€
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Barbital
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 57-44-3
Barbital is a barbiturate that has been used in the treatment of epilepsy, insomnia, and as a sedative. Barbital has been shown to have significant cytotoxicity against human serum. It also inhibits the synthesis of p-hydroxybenzoic acid by competing with the enzyme amide hydrolase. The fluorescence properties of barbital can be used to measure 5-HT concentrations in biological studies. Barbital is an inhibitor molecule for enzymes such as monoamine oxidase, which are found in the brain and other organs. The monosodium salt form of barbital is more soluble than other forms and has a lower toxicity level than other barbiturates.
Formula:C₈H₁₂N₂O₃
Purity:Min. 95%
Molecular weight:184.19 g/mol
Ref: 3D-FB18141
100g
778.00€
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500g
2,141.00€
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