CAS 57-66-9: Probenecid
Description:Probenecid, with the CAS number 57-66-9, is a pharmaceutical compound primarily used as a uricosuric agent to treat gout and hyperuricemia. It functions by inhibiting the renal tubular reabsorption of uric acid, thereby promoting its excretion and lowering serum uric acid levels. Probenecid is a white to off-white crystalline powder that is soluble in water and alcohol, with a melting point typically around 170-175°C. Its chemical formula is C13H17NO4S, and it has a molecular weight of approximately 273.35 g/mol. The compound is often administered orally and can be used in combination with other medications, such as penicillin, to prolong their effects by inhibiting their renal excretion. Probenecid may cause side effects, including gastrointestinal disturbances and hypersensitivity reactions. It is contraindicated in patients with certain renal conditions and should be used with caution in those with a history of kidney stones. Overall, Probenecid plays a significant role in managing conditions related to uric acid metabolism.
Formula:C13H19NO4S
InChI:InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
InChI key:InChIKey=DBABZHXKTCFAPX-UHFFFAOYSA-N
SMILES:O=C(O)C1=CC=C(C=C1)S(=O)(=O)N(CCC)CCC
- Synonyms:
- 4-((Dipropylamino)Sulfonyl)-Benzoicaci
- 4-(Dipropylaminosulfonyl)benzoic acid
- 4-(Dipropylsulfamoyl)Benzoate
- 4-(Dipropylsulfamoyl)Benzoicacid
- 4-(Dipropylsulfamoyl)benzoic acid
- 4-(N,N-Dipropylaminosulfonyl)benzoic acid
- 4-(N,N-Dipropylsulfamoyl)benzoic acid
- 4-[(Dipropylamino)sulfonyl]benzoic acid
- Apurina
- Benacen
- See more synonyms
- Benecid
- Benemid
- Benemide
- Benuryl
- Benzoic acid, 4-[(dipropylamino)sulfonyl]-
- Benzoic acid, p-(dipropylsulfamoyl)-
- Benzoicacid,4-((Dipropylamino)Sulfonyl)
- Col-Probenecid
- Colbenemid
- Nsc 18786
- Probecid
- Proben
- Probenecid acid
- Probenecida
- Probenecide
- Prolongine
- Synergid R
- Tubophan
- Uricosid
- p-(Dipropylsulfamoyl)benzoic acid
- p-(Dipropylsulfamyl)benzoic acid
