CAS 57-66-9

Probenecid

Description:

Probenecid, with the CAS number 57-66-9, is a pharmaceutical compound primarily used as a uricosuric agent to treat gout and hyperuricemia. It functions by inhibiting the renal tubular reabsorption of uric acid, thereby promoting its excretion and lowering serum uric acid levels. Probenecid is a white to off-white crystalline powder that is soluble in water and alcohol, with a melting point typically around 170-175°C. Its chemical formula is C13H17NO4S, and it has a molecular weight of approximately 273.35 g/mol. The compound is often administered orally and can be used in combination with other medications, such as penicillin, to prolong their effects by inhibiting their renal excretion. Probenecid may cause side effects, including gastrointestinal disturbances and hypersensitivity reactions. It is contraindicated in patients with certain renal conditions and should be used with caution in those with a history of kidney stones. Overall, Probenecid plays a significant role in managing conditions related to uric acid metabolism.

Formula: C₁₃H₁₉NO₄S

InChI: InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)

InChI key: InChIKey=DBABZHXKTCFAPX-UHFFFAOYSA-N

SMILES: S(N(CCC)CCC)(=O)(=O)C1=CC=C(C(O)=O)C=C1

Synonyms:

• 4-((Dipropylamino)Sulfonyl)-Benzoicaci
• 4-(Dipropylaminosulfonyl)benzoic acid
• 4-(Dipropylsulfamoyl)Benzoate
• 4-(Dipropylsulfamoyl)Benzoicacid
• 4-(Dipropylsulfamoyl)benzoic acid
• 4-(N,N-Dipropylaminosulfonyl)benzoic acid
• 4-(N,N-Dipropylsulfamoyl)benzoic acid
• 4-[(Dipropylamino)sulfonyl]benzoic acid
• Apurina
• Benacen
• Benecid
• Benemid
• Benemide
• Benuryl
• Benzoic acid, 4-[(dipropylamino)sulfonyl]-
• Benzoic acid, p-(dipropylsulfamoyl)-
• Benzoicacid,4-((Dipropylamino)Sulfonyl)
• Col-Probenecid
• Colbenemid
• Nsc 18786
• Probecid
• Proben
• Probenecid acid
• Probenecida
• Probenecide
• Prolongine
• Synergid R
• Tubophan
• Uricosid
• p-(Dipropylsulfamoyl)benzoic acid

Probenecid, 98%

CAS: 57-66-9

It is a uricosuric drug, that is, it increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and

Formula: C₁₃H₁₉NO₄S

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 285.36

Ref: 02-B20010

Probenecide, 1mg/ml in Methanol

CAS: 57-66-9

Color and Shape: Single Solution

Ref: LP-PRO-717-1LM

Probenecid

CAS: 57-66-9

Color and Shape: Neat

Ref: 61-FOR0657.00

PROBENECID CRS

CAS: 57-66-9

PROBENECID CRS

Formula: C₁₃H₁₉NO₄S

Color and Shape: Added Modified

Molecular weight: 285.3593

Ref: 41-P3000000

Probenecid

CAS: 57-66-9

Sulfonamides used as drugs

Formula: C₁₃H₁₉NO₄S

Color and Shape: White Off-White Fine Crystalline Powder

Molecular weight: 285.10348

Ref: 45-1563003

Probenecid

CAS: 57-66-9

Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.

Formula: C₁₃H₁₉NO₄S

Purity: 98.95% - 99.84%

Color and Shape: Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)

Molecular weight: 285.36

Ref: TM-T0457

Probenecid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Purity: ≥ 98.0% (dried basis)

Color and Shape: White crystalline powder

Molecular weight: 285.36

Ref: 7W-GP9170

Probenecid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Color and Shape: White To Off-White Solid

Molecular weight: 285.36

Ref: 4Z-P-301

Probenecid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Color and Shape: Neat

Molecular weight: 285.36

Ref: 04-C16289100

Probenecide

CAS: 57-66-9

Color and Shape: Neat

Ref: LP-PRO-717-10

Probenecid

Controlled Product

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Color and Shape: Neat

Molecular weight: 285.36

Ref: 86-MM0657.00

Probenecid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 285.36

Ref: 3B-P1975

Probenecid RS

CAS: 57-66-9

Color and Shape: White To Nearly White

Ref: 2K-1143000021

Probenecid

Controlled Product

CAS: 57-66-9

Applications Uricosuric.
References McKinney, S.E., et al.: J. Pharmacol. Exp. Ther., 102, 208 (1951), Israili, Z.H., et al.: J. Med. Chem., 15, 709 (1972), Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 10, 639 (1981), Cunningham, R.F., et al.: Clin. Pharmacokinet., 6, 135 (1981),

Formula: C₁₃H₁₉NO₄S

Color and Shape: White

Molecular weight: 285.36

Ref: TR-P755000

Probenecid

Controlled Product

CAS: 57-66-9

Organic anion transporter inhibitor; pannexin 1 channel inhibitor

Formula: C₁₃H₁₉NO₄S

Purity: Min. 97.5 Area-%

Color and Shape: White Powder

Molecular weight: 285.36 g/mol

Ref: 3D-FD27163

Probenecid - Bio-X ™

Controlled Product

CAS: 57-66-9

Probenecid is a uricosuric agent that is used to treat gout and hyperuricemia. This drug works by inhibiting the reabsorption of uric acid in the renal tubes which results in more uric acid being passed out in the urine. By lowering uric acid levels, Probenecid helps prevent the formation of uric acid crystals in joints, reducing the risk of gout attacks. This drug can also be used as an adjunct to antibacterial therapy.

Formula: C₁₃H₁₉NO₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 285.36 g/mol

Ref: 3D-BP166195

4-(dipropylsulfamoyl)benzoic acid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Purity: 98.0%

Color and Shape: Liquid, No data available.

Molecular weight: 285.36

Ref: 10-F358404

Probenecid

CAS: 57-66-9

Formula: C₁₃H₁₉NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 285.3593

Ref: IN-DA003TYN