CAS 570-63-8

3β,12α-Dihydroxy-5β-cholanoic acid

Description:

3β,12α-Dihydroxy-5β-cholanoic acid, also known as hyodeoxycholic acid, is a bile acid derivative characterized by its hydroxyl groups at the 3β and 12α positions on the steroid nucleus. This compound is a naturally occurring bile acid found in various species, including some mammals. It plays a role in the digestion and absorption of dietary fats and fat-soluble vitamins. The presence of hydroxyl groups enhances its solubility in water, facilitating its function in the gastrointestinal tract. Hyodeoxycholic acid exhibits a unique stereochemistry, contributing to its biological activity and interaction with bile acid receptors. It is also involved in the regulation of cholesterol metabolism and has potential implications in therapeutic applications related to liver function and metabolic disorders. The compound is typically studied in the context of its physiological roles and potential health benefits, as well as its structural analogs in medicinal chemistry.

Formula: C₂₄H₄₀O₄

InChI: InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17+,18-,19+,20+,21+,23+,24-/m1/s1

InChI key: InChIKey=KXGVEGMKQFWNSR-OFYXWCICSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (3β,5β,12α)-3,12-Dihydroxycholan-24-oic acid
• 3-Epideoxycholic acid
• 3b,12a-Dihydroxy-5b-cholan-24-oic acid
• 3β,12α-Dihydroxy-5β-cholanic acid
• 3β,12α-Dihydroxy-5β-cholanoic acid
• 3β,12α-Dihydroxycholanoic acid
• 3β-Deoxycholic acid
• 5β-Cholan-24-oic acid, 3β,12α-dihydroxy-
• 5β-Cholanic acid, 3β,12α-dihydroxy-
• 5β-Cholanic acid-3β,12α-diol
• Cholan-24-Oic Acid, 3,12-Dihydroxy-, (3Beta,5Beta,12Alpha)-

3-Epideoxycholic acid

CAS: 570-63-8

3-Epideoxycholic acid

Purity: ≥95%

Ref: 54-OR1038734

Cholic Acid Impurity 26

CAS: 570-63-8

Formula: C₂₄H₄₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 392.58

Ref: 4Z-C-5798

3-Epideoxycholic Acid

CAS: 570-63-8

3-Epideoxycholic Acid is a secondary bile acid, a microbial metabolite of Deoxycholic acid. It targets the FXR receptor on dendritic cells, anti-inflammatory.

Formula: C₂₄H₄₀O₄

Purity: 99.433%

Color and Shape: Solid

Molecular weight: 392.57

Ref: TM-T84944

3-epi-Deoxycholic Acid-d5

Controlled Product

CAS: 570-63-8

Applications 3-epi-Deoxycholic Acid-d5 is a labelled analogue of 3-Epideoxycholic Acid. 3-epi-Deoxycholic Acid-d5 is an intermediate in synthesizing Deoxycholic Acid-d5 (D232647), which is a labelled Cholic Acid (C432600) derivative used as a component in cell lysis buffers.
References Tuangtong, R. et al.: Dermatol. Surg., 36, 899 (2010); Araki, Y. et al.: Scand. J. Gast., 36, 533 (2001);

Formula: C₂₄H₃₅D₅O₄

Color and Shape: Off-White To Light Yellow

Molecular weight: 397.6

Ref: TR-D232727

(3β,​5β,​12α)​-3,​12-​Dihydroxycholan-​24-​oic Acid

Controlled Product

CAS: 570-63-8

Formula: C₂₄H₄₀O₄

Color and Shape: Neat

Molecular weight: 392.572

Ref: TR-D251110