CAS 570-78-5

(3α,5β,6α)-3,6-Dihydroxypregnan-20-one

Description:

(3α,5β,6α)-3,6-Dihydroxypregnan-20-one, commonly known as allopregnanolone, is a neuroactive steroid derived from progesterone. It is characterized by its hydroxyl groups at the 3 and 6 positions on the steroid nucleus, which contribute to its biological activity. This compound is known for its role in the central nervous system, where it acts as a positive modulator of the GABA-A receptor, influencing neuronal excitability and providing anxiolytic and sedative effects. Allopregnanolone is also involved in various physiological processes, including mood regulation, stress response, and neuroprotection. Its chemical structure includes a steroid backbone with specific stereochemistry, which is crucial for its interaction with biological targets. Additionally, it has been studied for its potential therapeutic applications in conditions such as depression, anxiety disorders, and neurodegenerative diseases. The substance is typically found in the human body, particularly during pregnancy, and its levels can fluctuate based on hormonal changes.

Formula: C₂₁H₃₄O₃

InChI: InChI=1/C21H34O3/c1-12(22)15-4-5-16-14-11-19(24)18-10-13(23)6-8-21(18,3)17(14)7-9-20(15,16)2/h13-19,23-24H,4-11H2,1-3H3/t13-,14+,15-,16+,17+,18+,19+,20-,21-/m1/s1

InChI key: InChIKey=HHUZGDMRRLQZIQ-PXWUZWBYSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](C(C)=O)CC4)[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Synonyms:

• (3Alpha,5Beta,6Alpha)-3,6-Dihydroxypregnan-20-One
• (3α,5β,6α)-3,6-Dihydroxypregnan-20-one
• 3-alpha,6-alpha-Dihydroxy-5-beta-pregnan-20-one
• 3alpha,6alpha-Dihydroxy-5beta-pregnan-20-one
• 3α,6α-Dihydroxy-20-oxo-5β-pregnane
• 3α,6α-Dihydroxy-5β-pregnan-20-one
• 3α,6α-Dihydroxy-5β-pregnane-20-one
• 5-beta-Pregnan-20-one, 3-alpha,6-alpha-dihydroxy-
• 5beta-Pregnan-20-one, 3alpha,6alpha-dihydroxy-
• 5β-Pregna-3α,6α-diol-20-one
• 5β-Pregnan-20-one, 3α,6α-dihydroxy-
• 5β-Pregnan-3α,6α-diol-20-one
• 5β-Pregnane-3α,6α-diol-20-one
• 6-alpha-Hydroxypregnanolone
• 6α-Hydroxypregnanolone
• Diolone
• Nsc 50920
• Pregnan-20-one, 3,6-dihydroxy-, (3-alpha,5-beta,6-alpha)- (9CI)
• Pregnan-20-one, 3,6-dihydroxy-, (3alpha,5beta,6alpha)- (9CI)
• Pregnan-20-one, 3,6-dihydroxy-, (3α,5β,6α)-
• Pregnan-3,6-diol-20-one
• 3ALPHA,6ALPHA-Dihydroxy-5B-pregnan-20-one
• 5-BETA-PREGNAN-3-ALPHA, 6-ALPHA-DIOL-20-ONE
• Einecs 209-333-8

(3-alfa,5-β,6-alfa)-3,6-Dihydroxypregnan-20-one

CAS: 570-78-5

Formula: C₂₁H₃₄O₃

Molecular weight: 334.50

Ref: 4Z-P-32141

5β-Pregnan-3α,6α-diol-20-one

Controlled Product

CAS: 570-78-5

5β-Pregnan-3α,6α-diol-20-one is an anticoagulant that inhibits the action of thrombin. It has been shown to inhibit the inflammatory response in a number of autoimmune diseases and inflammatory disorders. This drug also has a nitro group, which can be reduced to an hydroxyl group by reaction with sodium nitrite or other reducing agents. The antimicrobial properties of 5β-pregnan-3α,6α-diol-20-one are thought to be due to its ability to form particle aggregates with magnetic particles. These aggregates have an inhibitory effect on bacterial growth.

Formula: C₂₁H₃₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 334.49 g/mol

Ref: 3D-FP67238