CAS 57010-31-8

Tiapamil

Description:

Tiapamil is a chemical compound classified as a calcium channel blocker, primarily used in the treatment of cardiovascular conditions. It is known for its ability to inhibit the influx of calcium ions through L-type calcium channels, which helps to relax vascular smooth muscle and reduce blood pressure. Tiapamil exhibits antiarrhythmic properties, making it beneficial in managing certain types of cardiac arrhythmias. The compound is typically administered in a clinical setting and may be available in various formulations. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which can vary based on individual patient factors. Common side effects may include dizziness, headache, and gastrointestinal disturbances, although serious adverse effects are relatively rare. As with any medication, it is essential for healthcare providers to consider potential drug interactions and contraindications when prescribing Tiapamil. Overall, Tiapamil serves as an important therapeutic agent in the management of specific cardiovascular disorders, contributing to improved patient outcomes.

Formula: C₂₆H₃₇NO₈S₂

InChI: InChI=1S/C26H37NO8S2/c1-27(15-12-20-8-10-22(32-2)24(18-20)34-4)14-6-13-26(36(28,29)16-7-17-37(26,30)31)21-9-11-23(33-3)25(19-21)35-5/h8-11,18-19H,6-7,12-17H2,1-5H3

InChI key: InChIKey=ZROUQTNYPCANTN-UHFFFAOYSA-N

SMILES: C(CCN(CCC1=CC(OC)=C(OC)C=C1)C)C2(S(=O)(=O)CCCS2(=O)=O)C3=CC(OC)=C(OC)C=C3

Synonyms:

• 1,3-Dithiane-2-propanamine, 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-, 1,1,3,3-tetraoxide
• Tiapamil

Tiapamil Free Base

CAS: 57010-31-8

Tiapamil Free Base is a phenylethylamine derivative that acts as a calcium antagonist showing hemodynamic effects in patients with acute myocardial infarction.

Formula: C₂₆H₃₇NO₈S₂

Color and Shape: Solid

Molecular weight: 555.7

Ref: TM-T69078