CAS 57010-32-9

1,3-Dithiane-2-propanamine, 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-, 1,1,3,3-tetraoxide, hydrochloride (1:1)

Description:

1,3-Dithiane-2-propanamine, 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-, 1,1,3,3-tetraoxide, hydrochloride (1:1) is a complex organic compound characterized by its unique structural features, including a dithiane ring and multiple methoxy-substituted phenyl groups. The presence of the tetraoxide functional group suggests a high degree of oxidation, which may influence its reactivity and stability. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, enhancing its potential applications in biological systems. The compound's amine functionality indicates potential for interactions with biological receptors, making it of interest in medicinal chemistry. Its specific stereochemistry and substituent arrangement can significantly affect its pharmacological properties. However, detailed studies on its biological activity, toxicity, and pharmacokinetics would be necessary to fully understand its potential applications and safety profile. Overall, this compound represents a fascinating area of study within organic and medicinal chemistry.

Formula: C₂₆H₃₇NO₈S₂·ClH

InChI: InChI=1S/C26H37NO8S2.ClH/c1-27(15-12-20-8-10-22(32-2)24(18-20)34-4)14-6-13-26(36(28,29)16-7-17-37(26,30)31)21-9-11-23(33-3)25(19-21)35-5;/h8-11,18-19H,6-7,12-17H2,1-5H3;1H

InChI key: InChIKey=FEEDFNKRGAKOFI-UHFFFAOYSA-N

SMILES: C(CCN(CCC1=CC(OC)=C(OC)C=C1)C)C2(S(=O)(=O)CCCS2(=O)=O)C3=CC(OC)=C(OC)C=C3.Cl

Synonyms:

• 1,3-Dithiane-2-propanamine, 2-(3,4-dimethoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-N-methyl-, 1,1,3,3-tetraoxide, hydrochloride
• 1,3-Dithiane-2-propanamine, 2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-, 1,1,3,3-tetraoxide, hydrochloride (1:1)
• Dimeditiapramine
• Larocord
• N-[2-(3,4-dimethoxyphenyl)ethyl]-3-[2-(3,4-dimethoxyphenyl)-1,1,3,3-tetraoxido-1,3-dithian-2-yl]-N-methylpropan-1-aminium chloride
• Ro 11-1781
• Tiapamil HCl
• Tiapamil hydrochloride
• Tiapamil hydrochloride [USAN]
• m-Dithiane-2-propylamine, N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)-N-methyl-, 1,1,3,3-tetraoxide, hydrochloride
• ((3,4-Dimethoxyphenethyl)(2-(2,3-dimethoxyphenyl)-1,3-dithian-2-yl)propyl)methylammonium chloride 1,1,3,3-tetraoxide

Tiapamil hydrochloride

CAS: 57010-32-9

Tiapamil hydrochloride

Purity: ≥98%

Molecular weight: 592.16g/mol

Ref: 54-BUP04677

Tiapamil hydrochloride

CAS: 57010-32-9

Tiapamil hydrochloride is a drug that is used to treat cardiac conditions, such as chronic heart failure. Tiapamil hydrochloride binds to calcium and decreases the amount of calcium in the blood. This leads to a decrease in the force of contraction of the heart muscle and diastolic pressure, which are both associated with congestive heart failure. Tiapamil hydrochloride has been shown to reduce the risk of death and hospitalization due to cardiovascular causes by reducing myocardial infarction or papillary muscle dysfunction.
Tiapamil hydrochloride can cause drug interactions with other drugs that affect calcium levels, such as digoxin, phenytoin, or verapamil. It also has toxic effects on the kidneys and can lead to low glomerular filtration rate (GFR) or increased creatinine level in urine.

Formula: C₂₆H₃₇NO₈S₂

Purity: Min. 95%

Molecular weight: 555.7 g/mol

Ref: 3D-HCA01032

Tiapamil hydrochloride

CAS: 57010-32-9

Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity used in the study of angina pectoris.

Formula: C₂₆H₃₈ClNO₈S₂

Purity: 99.17%

Color and Shape: Solid

Molecular weight: 592.16

Ref: TM-T13154