CAS 57018-46-9

1-(4-azidophenyl)-2-bromoethan-1-one

Description:

1-(4-Azidophenyl)-2-bromoethan-1-one, with the CAS number 57018-46-9, is an organic compound characterized by the presence of both an azide group and a bromo substituent on its structure. This compound features a phenyl ring substituted at the para position with an azide group (-N3), which is known for its reactivity and utility in click chemistry. The bromo group is attached to an ethyl ketone moiety, contributing to its electrophilic nature. The presence of the ketone functional group indicates that it can participate in various chemical reactions, such as nucleophilic additions. The azide group can undergo thermal or photochemical decomposition, leading to the release of nitrogen gas and the formation of reactive intermediates. This compound is of interest in synthetic organic chemistry, particularly in the development of new materials and pharmaceuticals, due to its potential for further functionalization and its role in coupling reactions. Safety precautions should be observed when handling this compound, as azides can be hazardous.

Formula: C₈H₆BrN₃O

InChI: InChI=1S/C8H6BrN3O/c9-5-8(13)6-1-3-7(4-2-6)11-12-10/h1-4H,5H2

InChI key: InChIKey=LZJPDRANSVSGOR-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC=C(N=[N+]=[N-])C=C1

Synonyms:

• 1-(4-Azidophenyl)-2-Bromoethanone
• 2-Bromo-4′-azidoacetophenone
• 4-Azidophenacyl bromide
• 4′-Azido-2-bromoacetophenone
• Ethanone, 1-(4-azidophenyl)-2-bromo-
• p-Azidophenacetyl bromide
• p-Azidophenacyl bromide
• 1-(4-Azidophenyl)-2-bromoethan-1-one
• 1-(4-Azidophenyl)-2-bromo-ethanone
• 4'-Azido-α-bromoacetophenone
• 1-(4-Azidophenyl)-2-bromoethan-1-one, 4-(Bromoacetyl)phenyl azide
• 4-Azidophenacyl bromide powder

4-Azidophenacyl bromide powder

CAS: 57018-46-9

Formula: C₈H₆BrN₃O

Color and Shape: Solid

Molecular weight: 240.0567

Ref: IN-DA003TK4

4-Azidophenacyl bromide

CAS: 57018-46-9

4-Azidophenacyl bromide

Formula: C₈H₆BrN₃O

Purity: ≥95%

Color and Shape: pale yellow to pale beige solid

Molecular weight: 240.06g/mol

Ref: 54-OR2000T

p-Azidophenacyl Bromide

Controlled Product

CAS: 57018-46-9

Stability Light, Temperature and Moisture sensitive
Applications A versatile photolabile bifunctional reagent. Useful for investigating the active sites of sulfhydryl enzymes-particularly those which posess a particularly reactive cysteine residue at the active site. Used to study the nature of the ribosomal binding site of E. coli tRNAVal.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schwartz, I., et al.: Proc. Natl. Acad. Sci. USA, 71, 230 (1974)

Formula: C₈H₆BrN₃O

Color and Shape: Neat

Molecular weight: 240.06

Ref: TR-A920000

p-Azidophenacyl bromide

CAS: 57018-46-9

p-Azidophenacyl bromide is an enzyme form that catalyzes the hydrolysis of azides, such as nitrobenzene. It is chemically stable and can be used in human serum. The enzyme form has been shown to hydrolyze DNA with high specificity and low background. p-Azidophenacyl bromide also has antiviral properties against herpes simplex virus because it inhibits the synthesis of viral DNA. This enzyme form also binds to benzyl groups on the surface of cell membranes, which are part of a ternary complex formation with lysine residues and hydroxyl groups. p-Azidophenacyl bromide is present in mitochondria and cytochrome plasma mass spectrometry has shown that it is a mitochondrial cytochrome.

Formula: C₈H₆BrN₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 240.06 g/mol

Ref: 3D-FA18106

p-Azidophenacyl bromide

CAS: 57018-46-9

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 240.05999755859375

Ref: 10-F493852