CAS 57079-01-3

11-Maleimidoundecanoic acid

Description:

11-Maleimidoundecanoic acid is a chemical compound characterized by its unique structure, which includes a maleimide functional group and a long hydrocarbon chain. This compound is typically used in bioconjugation and as a crosslinking agent due to its ability to form stable covalent bonds with thiol groups. The presence of the maleimide moiety allows for selective reactions with sulfhydryl-containing molecules, making it valuable in various applications, including drug delivery, protein labeling, and the development of biomaterials. The long undecanoic acid chain contributes to its hydrophobic properties, influencing its solubility and interaction with biological membranes. Additionally, 11-Maleimidoundecanoic acid can be utilized in the synthesis of polymeric materials and in the modification of surfaces for enhanced biocompatibility. Its stability under physiological conditions and reactivity with thiols make it a versatile tool in chemical biology and materials science.

Formula: C₁₅H₂₃NO₄

InChI: InChI=1S/C15H23NO4/c17-13-10-11-14(18)16(13)12-8-6-4-2-1-3-5-7-9-15(19)20/h10-11H,1-9,12H2,(H,19,20)

InChI key: InChIKey=UVZTZBRGZXIBLZ-UHFFFAOYSA-N

SMILES: C(CCCCCCCCCC(O)=O)N1C(=O)C=CC1=O

Synonyms:

• 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid
• 11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoicacid
• 1H-pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-
• 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-undecanoic acid
• Am 10
• N-(10-Carboxydecyl)maleimide
• 11-Maleimidoundecanoic acid

11-Maleimidoundecanoic acid

CAS: 57079-01-3

The maleimide functional group can be used to conjugate a variety of biomolecules such as enzymes and DNA to the polymer chain. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy br

Formula: C₁₅H₂₃NO₄

Color and Shape: Powder, White to off-white

Molecular weight: 281.35

Ref: 02-046716

11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl);undecanoic acid

CAS: 57079-01-3

Formula: C₁₅H₂₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.3474

Ref: IN-DA00ECUS

11-Maleimidoundecanoic acid

CAS: 57079-01-3

11-Maleimidoundecanoic acid

Purity: ≥98%

Molecular weight: 281.35g/mol

Ref: 54-BUP18811

11-Maleimidoundecanoic Acid

CAS: 57079-01-3

11-Maleimidoundecanoic Acid

Purity: 97%

Molecular weight: 281.35g/mol

Ref: 54-OR1009326

11-Maleimidoundecanoic acid

CAS: 57079-01-3

11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.

Formula: C₁₅H₂₃NO₄

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 281.35

Ref: TM-T17324

11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid

CAS: 57079-01-3

Formula: C₁₅H₂₃NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 281.352

Ref: 10-F324176

11-Maleimidoundecanoic Acid

Controlled Product

CAS: 57079-01-3

Applications A sulfhydryl reactive heterobifunctional crosslinking reagent.Spacer Arm: 15.7 Angstroms
References Rich, D., et al.: J. Med. Chem., 18, 1004 (1975), Moroder, L., et al.: BioPolymers, 22, 481 (1983)

Formula: C₁₅H₂₃NO₄

Color and Shape: Neat

Molecular weight: 281.35

Ref: TR-M151350