CAS 57109-90-7

Clorazepate Dipotassium

Description:

Clorazepate dipotassium is a benzodiazepine derivative primarily used as an anxiolytic and anticonvulsant medication. It is characterized by its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to sedative, anxiolytic, muscle relaxant, and anticonvulsant properties. The substance is typically administered in its dipotassium salt form, which improves its solubility and bioavailability. Clorazepate dipotassium is often prescribed for the treatment of anxiety disorders, alcohol withdrawal symptoms, and certain types of seizures. It is important to note that, like other benzodiazepines, it may lead to dependence and withdrawal symptoms upon discontinuation after prolonged use. Common side effects can include drowsiness, dizziness, and cognitive impairment. Due to its potential for abuse and dependence, clorazepate dipotassium is classified as a controlled substance in many jurisdictions, necessitating careful monitoring by healthcare professionals during treatment.

Formula: C₁₆H₁₁ClK₂N₂O₄

InChI: InChI=1S/C16H11ClN2O3.2K.H2O/c17-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)19-14(16(21)22)15(20)18-12;;;/h1-8,14H,(H,18,20)(H,21,22);;;1H2/q;;+1;/p-1

InChI key: InChIKey=TVVIGDFTYHGWSG-UHFFFAOYSA-M

SMILES: [K]O.C(O)(=O)C1N=C(C=2C(NC1=O)=CC=C(Cl)C2)C3=CC=CC=C3.[K]

Synonyms:

• 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, monopotassium salt, compd. with potassium hydroxide (1:1)
• 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, monopotassium salt, compd. with potassium hydroxide (K(OH)) (1:1)
• 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, potassium salt, compd. with potassium hydroxide (K(OH)) (1:1:1)
• 1H-1,4-benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, hydroxide, potassium salt (1:1:2)
• 4306Cb
• 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
• Ab 35616
• Abbott 35616
• Apo-Clorazepate
• Azene
• Belseren
• Bipotassium chlorazepate
• Cb 4306
• Chlorazepate
• Chlorazepate Dipotassium
• Chlorazepate dipotassic
• Clorazepate potassium
• Cm 4306
• Dikalium chlorazepate
• Dipotassium chlorazepate
• Dipotassium clorazepate
• Gen-xene
• Mendon
• Nevracten
• Novo-Clopate
• Nu-Clopate
• Potassium hydroxide (K(OH)), compd. with 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid monopotassium salt (1:1)
• Potassium hydroxide, compd. with 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid monopotassium salt (1:1)
• Tencilan
• Tr 19119
• Transene
• Tranxene
• Tranxilen
• Tranxilene
• Tranxilium
• Tranzene
• [2-Phenyl-2-(2-amino-5-chlorophenyl)-1-azavinyl]malonic acid
• potassium 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylate hydroxypotassium (1:1:1)

Clorazepate.dipotassium.monohydrate

Controlled Product

CAS: 57109-90-7

Color and Shape: Neat

Ref: LP-CLR-120-HY-10

Clorazepate Dipotassium

Controlled Product

CAS: 57109-90-7

Applications Anxiolytic. Controlled substance (depressant).
References Cone, E., et al.: J. Pharm. Sci., 73, 243 (1984), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Beyer, J., et al.: Ther. Drug Monit., 27, 151 (2005),

Formula: C₁₆H₁₀ClN₂O₃·HKO·K

Color and Shape: White To Light Yellow

Molecular weight: 408.92

Ref: TR-C587365

Clorazepate Dipotassium (1 mg/ml in Methanol)

Controlled Product

CAS: 57109-90-7

Formula: C₁₆H₁₀ClN₂O₃·HKO·K

Color and Shape: Colourless

Molecular weight: 408.92

Ref: TR-KIT4162

Clorazepic acid dipotasium salt

Controlled Product

CAS: 57109-90-7

Please enquire for more information about Clorazepic acid dipotasium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₆H₁₁ClK₂N₂O₄

Molecular weight: 408.92 g/mol

Ref: 3D-C-2990

Clorazepic acid dipotasium salt

Controlled Product

CAS: 57109-90-7

Clorazepic acid dipotasium salt is a benzodiazepine with anticonvulsant and anxiolytic activity. It is metabolized to clorazepate, which has a longer half-life than the parent drug. Clorazepic acid dipotasium salt can be administered orally, intravenously, or intramuscularly. The drug is not active when taken orally and must be converted to clorazepate before it can exert its effects. Clorazepic acid dipotasium salt has been shown to have minimal toxicity in humans and animals. This drug has been shown to have a dose-dependent effect on δ receptors and serotonergic activity, but does not affect dopamine receptors or histamine H1 receptors. Clorazepic acid dipotasium salt binds to the benzodiazepine receptor site in the brain and decreases the frequency of seizures by inducing sedation

Formula: C₁₆H₁₁ClK₂N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 408.92 g/mol

Ref: 3D-FC20518

DIPOTASSIUM CLORAZEPATE MONOHYDRATE CRS - * PSY

Controlled Product

CAS: 57109-90-7

DIPOTASSIUM CLORAZEPATE MONOHYDRATE CRS - * PSY

Ref: 41-Y0002276

Clorazepate Dipotassium CIV

Controlled Product

CAS: 57109-90-7

Alprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) only

Formula: C₁₆H₁₁ClK₂N₂O₄

Color and Shape: White Light Yellow Crystalline Powder

Molecular weight: 407.96815

Ref: 45-1140509