CAS 57117-44-9

1,2,3,6,7,8-Hexachlorodibenzofuran

Description:

1,2,3,6,7,8-Hexachlorodibenzofuran (CAS 57117-44-9) is a chlorinated aromatic compound belonging to the dibenzofuran family, characterized by the presence of six chlorine atoms attached to its dibenzofuran structure. This compound is typically a white to off-white solid and is known for its persistence in the environment, as well as its potential for bioaccumulation in living organisms. It is classified as a polychlorinated dibenzofuran (PCDF), which are known for their toxicological effects, including carcinogenicity and endocrine disruption. The compound is primarily formed as a byproduct in industrial processes, particularly in the production of chlorinated compounds and during combustion of organic materials. Due to its environmental persistence and potential health risks, 1,2,3,6,7,8-Hexachlorodibenzofuran is subject to regulatory scrutiny and monitoring. Its detection in environmental samples often raises concerns regarding contamination and ecological impact, necessitating further research into its behavior and effects in various ecosystems.

Formula: C₁₂H₂Cl₆O

InChI: InChI=1S/C12H2Cl6O/c13-4-1-3-7-6(2-5(14)8(15)10(7)17)19-12(3)11(18)9(4)16/h1-2H

InChI key: InChIKey=JEYJJJXOFWNEHN-UHFFFAOYSA-N

SMILES: ClC1=C2C=3C(OC2=CC(Cl)=C1Cl)=C(Cl)C(Cl)=C(Cl)C3

Synonyms:

• Dibenzofuran, 1,2,3,6,7,8-hexachloro
• 1,2,3,6,7,8-Hexachlorodibenzofuran
• 1,2,3,6,7,8-HxCDF
• 2,3,4,7,8,9-Hexachlorodibenzofuran
• F 121
• Pcdf 121

1,2,3,6,7,8-Hexachlorodibenzofuran

CAS: 57117-44-9

Formula: C₁₂H₂Cl₆O

Color and Shape: Solid

Molecular weight: 374.8617

Ref: IN-DA003APX

1,2,3,6,7,8-Hexachlorodibenzofuran

CAS: 57117-44-9

1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.

Formula: C₁₂H₂Cl₆O

Color and Shape: Solid

Molecular weight: 374.86

Ref: TM-T203643

1,2,3,6,7,8-Hexachlorodibenzofuran

CAS: 57117-44-9

Formula: C₁₂H₂Cl₆O

Molecular weight: 374.87

Ref: 4Z-B-104007

1,2,3,6,7,8-Hexachlorodibenzofuran

CAS: 57117-44-9

Applications 1,2,3,6,7,8-Hexachlorodibenzofuran, is a toxic polychlorinated dibenzofurans (PCDD/F), detected in domestic meat and poultry. It can be used as purified standards for analytical, toxic, and biological studies of these environmental contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huwe, J., et al.: Food Addit. Contam., 21, 182 (2004), Llobet, J., et al.: Toxicol. Lett., 178, 117 (2008); Feil, V., et al.: J. Agric. Food Chem., 48, 6163 (2000); Safe, S. H., et al.: J. Agric. Food Chem., 32, 68 (1984);

Formula: C₁₂H₂Cl₆O

Color and Shape: Neat

Molecular weight: 374.86

Ref: TR-H265100