CAS 571188-59-5

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Description:

Tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate, identified by its CAS number 571188-59-5, is a chemical compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. This compound features a tert-butyl ester group, contributing to its lipophilicity and potential for biological activity. The presence of a 6-aminopyridine moiety suggests that it may interact with various biological targets, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The carboxylate functional group indicates that it can participate in hydrogen bonding and ionic interactions, which may enhance its solubility and reactivity. Additionally, the compound's structural features may influence its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME). Overall, tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a versatile compound with potential applications in drug discovery and development, particularly in targeting neurological or psychiatric disorders.

Formula: C₁₄H₂₂N₄O₂

InChI: InChI=1S/C14H22N4O2/c1-14(2,3)20-13(19)18-8-6-17(7-9-18)11-4-5-12(15)16-10-11/h4-5,10H,6-9H2,1-3H3,(H2,15,16)

InChI key: InChIKey=RMULRXHUNOVPEI-UHFFFAOYSA-N

SMILES: C(OC(C)(C)C)(=O)N1CCN(CC1)C=2C=CC(N)=NC2

Synonyms:

• 1-Boc-4-(6-Aminopyridin-3-Yl)Piperazine
• 1-Piperazinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester
• 4-(6-Aminopyridin-3-yl)-1-Boc-piperazine
• 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
• Otava-Bb 1207229
• Palbociclib Intermediate-1
• Palbociclib intermediate
• Tert-Butyl 4-(6-Aminopyridin-3-Yl)Piperazine-1-Carboxylate
• tert-Butyl-4-(6-aminopyridin-3-yl)piperazin-1-carboxylat
• tert-Butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate
• tert-butyl  4-(6-amino-3-pyridyl)piperazine-1-carboxylate

4-(6-Amino-3-pyridyl)-1-Boc-piperazine, 97%

CAS: 571188-59-5

4-(6-Amino-3-pyridyl)-1-Boc-piperazine is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar produc

Formula: C₁₄H₂₂N₂O₄

Purity: 97%

Molecular weight: 278.35

Ref: 02-H54315

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

CAS: 571188-59-5

Formula: C₁₄H₂₂N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 278.3501

Ref: IN-DA00371S

6-(6-Aminopyridin-3-yl)piperazine, N1-BOC protected

CAS: 571188-59-5

6-(6-Aminopyridin-3-yl)piperazine, N1-BOC protected

Purity: 98%

Color and Shape: Brown Solid

Molecular weight: 278.35g/mol

Ref: 54-OR51957

Ribociclib Impurity 1

CAS: 571188-59-5

Formula: C₁₄H₂₂N₄O₂

Molecular weight: 278.36

Ref: 4Z-R-128007

1-Boc-4-(6-aminopyridin-3-yl)piperazine

Controlled Product

CAS: 571188-59-5

Applications 1-Boc-4-(6-aminopyridin-3-yl)piperazine is used to prepare pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of cyclin-dependent kinases 4 and 6.
References Toogood, P., et al.: J. Med. Chem., 48, 2388 (2005); Cho, Y., et al.: J. Med. Chem., 53, 7938 (2010)

Formula: C₁₄H₂₂N₄O₂

Color and Shape: Neat

Molecular weight: 278.35

Ref: TR-B621160

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

CAS: 571188-59-5

Formula: C₁₄H₂₂N₄O₂

Purity: 95%

Color and Shape: Solid, Beige crystalline powder

Molecular weight: 278.356

Ref: 10-F226455

tert-Butyl 4-(6-Amino-3-pyridyl)piperazine-1-carboxylate

CAS: 571188-59-5

Formula: C₁₄H₂₂N₄O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 278.36

Ref: 3B-B4669

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

CAS: 571188-59-5

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is an organic compound that can be synthesized by the reduction of 5-bromo-2-nitro pyridine with a palladium catalyst. It has been shown to inhibit the growth of cancer cells in vitro and in vivo, and is being investigated as a potential treatment for breast cancer.

Formula: C₁₄H₂₂N₄O₂

Purity: Min. 95%

Molecular weight: 278.35 g/mol

Ref: 3D-FB29531

Ribociclib Related Compound 1

CAS: 571188-59-5

Formula: C₁₄H₂₂N₄O₂

Molecular weight: 278.36

Ref: ST-EA-CP-R48044