(R)-Penbutolol Hydrochloride is a beta-blocker primarily used in the treatment of hypertension and certain types of heart conditions. It is a chiral compound, with the (R)-enantiomer being the active form that exhibits pharmacological effects. The substance functions by blocking beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Its chemical structure includes a butanol side chain, which contributes to its lipophilicity, allowing for effective absorption and distribution in the body. The hydrochloride salt form enhances its solubility in water, facilitating its use in pharmaceutical formulations. Commonly administered orally, (R)-Penbutolol Hydrochloride may also exhibit additional properties such as mild intrinsic sympathomimetic activity, which can influence its therapeutic profile. Side effects may include fatigue, dizziness, and gastrointestinal disturbances, typical of beta-blockers. As with any medication, it is essential to use it under medical supervision to manage potential interactions and contraindications effectively.

(R)-Penbutolol Hydrochloride

57130-27-5: (R)-Penbutolol Hydrochloride is a beta-blocker primarily used in the treatment of hypertension and certain types of heart conditions. It is a chiral compound, with the (R)-enantiomer being the active form that exhibits pharmacological effects. The substance functions by blocking beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Its chemical structure includes a butanol side chain, which contributes to its lipophilicity, allowing for effective absorption and distribution in the body. The hydrochloride salt form enhances its solubility in water, facilitating its use in pharmaceutical formulations. Commonly administered orally, (R)-Penbutolol Hydrochloride may also exhibit additional properties such as mild intrinsic sympathomimetic activity, which can influence its therapeutic profile. Side effects may include fatigue, dizziness, and gastrointestinal disturbances, typical of beta-blockers. As with any medication, it is essential to use it under medical supervision to manage potential interactions and contraindications effectively.

<p>Applications The R-enantiomer of Penbutolol (P220500).<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>

CAS 57130-27-5

(R)-Penbutolol Hydrochloride

(R)-Penbutolol Hydrochloride

Ref: TR-P220490