CAS 5714-00-1

Acetophenazine maleate

Description:

Acetophenazine maleate is a chemical compound that belongs to the class of phenothiazine derivatives, which are primarily known for their antipsychotic properties. It is characterized by its molecular structure, which includes a phenothiazine core linked to an acetophenone moiety. The maleate salt form indicates that it is combined with maleic acid, enhancing its solubility and stability for pharmaceutical applications. Acetophenazine maleate is typically used in the treatment of various psychiatric disorders, exhibiting properties such as sedation and antiemetic effects. The compound acts by antagonizing dopamine receptors in the central nervous system, which is a common mechanism among antipsychotic medications. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are influenced by its chemical structure, and it may exhibit side effects typical of phenothiazines, such as sedation, extrapyramidal symptoms, and anticholinergic effects. As with any pharmaceutical compound, its use should be monitored by healthcare professionals to manage potential adverse effects and interactions with other medications.

Formula: C₅₃H₆₄N₆O₁₁S₂

InChI: InChI=1/C23H29N3O2S.2C4H4O4/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27;2*5-3(6)1-2-4(7)8/h2-3,5-8,17,27H,4,9-16H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI key: InChIKey=JVMBOHDUHCHGOE-BTJKTKAUSA-N

SMILES: C(CCN1CCN(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(C(C)=O)C3.C(=C\C(O)=O)\C(O)=O

Synonyms:

• 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone di[(2Z)-but-2-enedioate] (salt)
• Acephenazine dimaleate
• Acetophenazine dimaleate
• Acetophenazine maleate
• Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:2)
• Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:2) (salt)
• Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (Z)-2-butenedioate (1:2) (salt)
• Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, dimaleate
• Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, maleate
• Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, maleate (1:2) (salt)
• NSC 169180
• NSC 70600
• Phentoxate
• Sch 6673
• Tindal
• Tindala
• ACETOPHENAZINE MALEATE (200 MG)
• 1-(10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-10h-phenothiazin-2-yl)eth
• 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethylketon
• Acetophenazine dimaleate salt
• ketone,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethyl
• 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl ketone maleate (1:2) (salt)
• 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl methyl ketone
• 1-(2-hydroxyethyl)-4-(3-(2-acetyl-10-phenothiazinyl)propyl)piperazinedimalea
• 2-acetyl-10-[3-[4-(2-hydroxyethyl)piperazinyl]propyl]-10H-phenothiazine dimaleate
• acetophenazinemaleate
• 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl ketone dimaleate
• sch6673
• 2-acetyl-10-(3-(4-(beta-hydroxyethyl)piperazinyl)propyl)phenothiazinedimalea
• ketone,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethyl,dimaleate
• ACETOPHENZAINEMALEATE

Acetophenazine dimaleate

CAS: 5714-00-1

Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.

Formula: C₃₁H₃₇N₃O₁₀S

Purity: 99.39% - 99.48%

Color and Shape: Solid

Molecular weight: 643.71

Ref: TM-T10232

ACETOPHENAZINE MALEATE

CAS: 5714-00-1

Formula: C₃₁H₃₇N₃O₁₀S

Purity: 98%

Color and Shape: Solid

Molecular weight: 643.7046

Ref: IN-DA00EF3T

Acetophenazine dimaleate

CAS: 5714-00-1

Acetophenazine dimaleate

Purity: ≥98%

Molecular weight: 643.71g/mol

Ref: 54-BUP05761

Acetophenazine Maleate

CAS: 5714-00-1

Formula: C₂₃H₂₉N₃O₂SC₄H₄O₄

Color and Shape: Neat

Molecular weight: 643.70

Ref: 86-MM1725.00

Acetophenazine dimaleate

Controlled Product

CAS: 5714-00-1

Stability Hygroscopic
Applications Antipsychotic.
References Schafer, E.W., et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972),

Formula: C₂₃H₂₉N₃O₂S·2C₄H₄O₄

Color and Shape: Neat

Molecular weight: 643.70

Ref: TR-A163930