CAS 5714-00-1: Acetophenazine maleate
Description:Acetophenazine maleate is a chemical compound that belongs to the class of phenothiazine derivatives, which are primarily known for their antipsychotic properties. It is characterized by its molecular structure, which includes a phenothiazine core linked to an acetophenone moiety. The maleate salt form indicates that it is combined with maleic acid, enhancing its solubility and stability for pharmaceutical applications. Acetophenazine maleate is typically used in the treatment of various psychiatric disorders, exhibiting properties such as sedation and antiemetic effects. The compound acts by antagonizing dopamine receptors in the central nervous system, which is a common mechanism among antipsychotic medications. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are influenced by its chemical structure, and it may exhibit side effects typical of phenothiazines, such as sedation, extrapyramidal symptoms, and anticholinergic effects. As with any pharmaceutical compound, its use should be monitored by healthcare professionals to manage potential adverse effects and interactions with other medications.
Formula:C23H29N3O2S·2C4H4O4
InChI:InChI=1S/C23H29N3O2S.C4H4O4/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27;5-3(6)1-2-4(7)8/h2-3,5-8,17,27H,4,9-16H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=JVMBOHDUHCHGOE-BTJKTKAUSA-N
SMILES:O=C(O)C=CC(=O)O.O=C(C1=CC=C2SC=3C=CC=CC3N(C2=C1)CCCN4CCN(CCO)CC4)C
- Synonyms:
- 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethanone di[(2Z)-but-2-enedioate] (salt)
- Acephenazine dimaleate
- Acetophenazine dimaleate
- Acetophenazine maleate
- Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:2)
- Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (2Z)-2-butenedioate (1:2) (salt)
- Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (Z)-2-butenedioate (1:2) (salt)
- Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, dimaleate
- Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, maleate
- Ketone, 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl, maleate (1:2) (salt)
- See more synonyms
- NSC 169180
- NSC 70600
- Phentoxate
- Sch 6673
- Tindal
- Tindala
