CAS 57149-08-3

1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-, hydrochloride (1:2)

Description:

1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-, hydrochloride (1:2) is a chemical compound characterized by its complex structure, which includes a piperazine ring, an ethanol moiety, and aromatic groups. This compound is typically a white to off-white solid and is soluble in water and organic solvents, reflecting its polar and non-polar characteristics due to the presence of both hydrophilic and hydrophobic components. The hydrochloride salt form indicates that it is a protonated species, enhancing its solubility and stability in aqueous environments. It may exhibit biological activity, potentially acting as a pharmacological agent, although specific biological properties would depend on its interaction with biological targets. The presence of methoxy and naphthyl groups suggests potential for interactions with various receptors or enzymes, making it of interest in medicinal chemistry. As with many piperazine derivatives, it may also possess psychoactive properties, warranting further investigation into its pharmacodynamics and pharmacokinetics. Safety and handling precautions should be observed due to its chemical nature.

Formula: C₂₄H₃₀Cl₂N₂O₃

InChI: InChI=1S/C24H28N2O3.2ClH/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23;;/h2-12,20,27H,13-18H2,1H3;2*1H

InChI key: InChIKey=HZVCEQMJXMUXJF-UHFFFAOYSA-N

SMILES: O(CC(CN1CCN(CC1)C2=C(OC)C=CC=C2)O)C=3C4=C(C=CC3)C=CC=C4.Cl

Synonyms:

• Naftopidil dihydrochloride
• 1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-, hydrochloride (1:2)
• 1-Piperazineethanol, 4-(2-methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-, dihydrochloride
• piperazin-1-yl)
• 4-(2-METHOXYPHENYL)-A-[(1-NAPHTHALENYLOXY)METHYL]-1-PIPERAZINEETHANOL, DIHYDROCHLORIDE
• 3-[(4-methylpiperazin-1-yl)methyl]quinazolin-4-one dihydrochloride
• 4-(2-Methoxyphenyl)-a-[(1-naphthalenyloxy)methyl]-1-piperazineethanol,2HCl
• Naftopidil DiHCl
• NAFTOPIDIL DIHYDROCHLORIDE USP/EP/BP
• KT-611 2HCl
• propan-2-ol dihydrochloride
• NAFTOPIDIL 2HCL
• KT-611 DIHYDROCHLORIDE
• -3-(naphthalen-1-yloxy)
• 4-(2-METHOXYPHENYL)-ALPHA-([1-NAPHTHALENYLYOXY]METHYL)-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
• 1-(4-(2-Methoxyphenyl)
• Naftopidil HCL
• 1-[4-(2-Methoxyphenyl)-1-piperazinyl]-3-(1-naphthoxy)-2-propanol dihydrochloride

Naftopidil dihydrochloride

CAS: 57149-08-3

Formula: C₂₄H₃₀Cl₂N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 465.4126

Ref: IN-DA00E94K

1-[4-(2-Methoxyphenyl)Piperazin-1-yl]-3-Naphthalen-1-Yloxypropan-2-ol;Dihydrochloride

CAS: 57149-08-3

1-[4-(2-Methoxyphenyl)Piperazin-1-yl]-3-Naphthalen-1-Yloxypropan-2-ol;Dihydrochloride

Purity: 98%

Molecular weight: 465.4g/mol

Ref: 54-OR1025055

Naftopidil dihydrochloride

CAS: 57149-08-3

Naftopidil dihydrochloride

Purity: ≥98%

Molecular weight: 465.41g/mol

Ref: 54-BUP14780

Naftopidil dihydrochloride

CAS: 57149-08-3

Formula: C₂₄H₂₈N₂O₃

Molecular weight: 392.49

Ref: 7W-GP9111

Naftopidil dihydrochloride

CAS: 57149-08-3

Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

Formula: C₂₄H₂₈N₂O₃·2HCl

Purity: 99.76%

Color and Shape: White Solid

Molecular weight: 465.41

Ref: TM-T6600

Naftopidil dihydrochloride

CAS: 57149-08-3

α1-adrenoceptor antagonist

Formula: C₂₄H₂₈N₂O₃•(HCl)₂

Purity: Min. 95%

Color and Shape: Solid.

Molecular weight: 465.41 g/mol

Ref: 3D-FN36633