CAS 5719-85-7

Hydroxytolbutamide

Description:

Hydroxytolbutamide, with the CAS number 5719-85-7, is a chemical compound that belongs to the class of sulfonylureas, which are primarily used in the management of type 2 diabetes. It functions as an oral hypoglycemic agent, promoting insulin secretion from the pancreas and thereby helping to lower blood glucose levels. The compound is characterized by its ability to enhance the sensitivity of peripheral tissues to insulin, contributing to improved glucose uptake. Hydroxytolbutamide is typically administered in a tablet form and is known for its relatively low side effect profile compared to other diabetes medications. Its chemical structure includes a hydroxyl group, which is significant for its biological activity. As with many sulfonylureas, it is essential to monitor patients for potential hypoglycemia and other metabolic effects. The pharmacokinetics of hydroxytolbutamide involve absorption, distribution, metabolism, and excretion, which are critical for determining dosing regimens and understanding its therapeutic efficacy.

Formula: C₁₂H₁₈N₂O₄S

InChI: InChI=1S/C12H18N2O4S/c1-2-3-8-13-12(16)14-19(17,18)11-6-4-10(9-15)5-7-11/h4-7,15H,2-3,8-9H2,1H3,(H2,13,14,16)

InChI key: InChIKey=SJRHYONYKZIRPM-UHFFFAOYSA-N

SMILES: S(NC(NCCCC)=O)(=O)(=O)C1=CC=C(CO)C=C1

Synonyms:

• 1-Butyl-3-(p-hydroxymethylphenyl)sulfonylurea
• 1-Butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea
• 2-[(4-fluorophenyl)amino]-5-[(4-nitrophenyl)methylidene]-1,3-thiazol-4(5H)-one
• Benzenesulfonamide, N-[(butylamino)carbonyl]-4-(hydroxymethyl)-
• Hydroxymethylcarbutamide
• Hydroxymethyltolbutamide
• Hydroxytolbutamide
• N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide
• N-(butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide
• N-[(Butylamino)carbonyl]-4-(hydroxymethyl)benzenesulfonamide
• Urea, 1-butyl-3-[(α-hydroxy-p-tolyl)sulfonyl]-

4-Hydroxytolbutamide

CAS: 5719-85-7

Formula: C₁₂H₁₈N₂O₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 286.3473

Ref: IN-DA00E8VI

Hydroxy Tolbutamide-d9

CAS: 5719-85-7

Formula: C₁₂H₉D₉N₂O₄S

Molecular weight: 295.41

Ref: 4Z-T-042

Hydroxy Tolbutamide

CAS: 5719-85-7

Formula: C₁₂H₁₈N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 286.35

Ref: 4Z-T-041

N-(Butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide

CAS: 5719-85-7

N-(Butylcarbamoyl)-4-(hydroxymethyl)benzenesulfonamide

Purity: 99%

Molecular weight: 286.35g/mol

Ref: 54-OR1074559

4-Hydroxytolbutamide

CAS: 5719-85-7

4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.

Formula: C₁₂H₁₈N₂O₄S

Purity: 98%

Color and Shape: White To Off-White

Molecular weight: 286.35

Ref: TM-T14040

4-Hydroxytolbutamide

CAS: 5719-85-7

Formula: C₁₂H₁₈N₂O₄S

Molecular weight: 286.35

Ref: 7W-GL7772

Hydroxy Tolbutamide

CAS: 5719-85-7

Formula: C₁₂H₁₈N₂O₄S

Color and Shape: White

Molecular weight: 286.35

Ref: TR-H969850

Hydroxy tolbutamide

CAS: 5719-85-7

Hydroxy tolbutamide is a drug with an unknown mechanism of action. It has been shown to inhibit the transcription-polymerase chain reaction and human serum in vitro. This drug may be used as a marker for renal disease, as it has been shown to increase the level of magnesium in urine and reduce the rate of protein synthesis in rat liver microsomes. Hydroxy tolbutamide also inhibits receptor activity, which may be due to its ability to inhibit the metabolic rate.

Formula: C₁₂H₁₈N₂O₄S

Purity: Min. 95%

Molecular weight: 286.35 g/mol

Ref: 3D-FH24142

Hydroxy Tolbutamide-d9 Sodium Salt

Controlled Product

CAS: 5719-85-7

Formula: C₁₂D₉H₈N₂NaO₄S

Color and Shape: Neat

Molecular weight: 317.385

Ref: TR-H969853

Hydroxy tolbutamide

CAS: 5719-85-7

Formula: C₁₂H₁₈N₂O₄S

Molecular weight: 286.35

Ref: ST-EA-CP-T75003