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CAS 572-59-8

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Epiquinidine

Description:
Epiquinidine is a chemical compound classified as an antiarrhythmic agent, primarily used in the treatment of certain types of cardiac arrhythmias. It is a stereoisomer of quinidine, which means it has a similar structure but differs in the spatial arrangement of atoms. Epiquinidine is known for its ability to block sodium channels, thereby stabilizing the cardiac cell membrane and reducing excitability. The compound has a molecular formula that includes carbon, hydrogen, nitrogen, and oxygen, reflecting its organic nature. Epiquinidine is typically administered in its salt form, enhancing its solubility and bioavailability. Its pharmacological effects include prolonging the action potential duration and refractory period in cardiac tissues, which can help restore normal heart rhythm. However, like many antiarrhythmic drugs, it may have side effects, including gastrointestinal disturbances and potential cardiotoxicity, necessitating careful monitoring during use. Overall, Epiquinidine plays a significant role in managing arrhythmias, although its use must be balanced with the risk of adverse effects.
Formula:C20H24N2O2
InChI:InChI=1/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20+/m0/s1
InChI key:InChIKey=LOUPRKONTZGTKE-AFHBHXEDSA-N
SMILES:[C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H]
Synonyms:
  • 9-Epiquinidine
  • 9-epi-Quinidine
  • Cinchonan-9-al, 6'-methoxy-, (9R)-
  • Cinchonan-9-ol, 6′-methoxy-, (9R)-
  • Epiquinidine
  • Icq 12
  • (9R)-6′-Methoxycinchonan-9-ol
  • (R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
  • (9R)-
  • (R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol
  • See more synonyms
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Found 3 products.
  • Epiquinidine

    CAS:
    <p>Epiquinidine</p>
    Purity:98%

    Ref: 54-OR1036632

    10mg
    1,316.00€
  • 9-epi-Quinidine

    Controlled Product
    CAS:
    Formula:C20H24N2O2
    Color and Shape:Neat
    Molecular weight:324.417

    Ref: TR-Q685005

    5mg
    122.00€
    25mg
    542.00€
  • Epiquinidine

    CAS:
    <p>Epiquinidine, an analogue of quinine, serves as an agonist for ggTas2r1, exhibiting activation at concentrations of 10 μM or higher.</p>
    Formula:C20H24N2O2
    Color and Shape:Solid
    Molecular weight:324.424

    Ref: TM-T40657

    ne
    Discontinued
    Discontinued product