CAS 57202-76-3

6-methyl-8-[(methylsulfanyl)methyl]-1,2-didehydro-2,3-dihydroergoline

Description:

6-Methyl-8-[(methylsulfanyl)methyl]-1,2-didehydro-2,3-dihydroergoline, with the CAS number 57202-76-3, is a chemical compound belonging to the class of ergoline derivatives. This substance features a complex bicyclic structure characteristic of ergoline alkaloids, which are known for their diverse biological activities. The presence of a methylsulfanyl group indicates that it contains a sulfur atom bonded to a methyl group, which can influence its reactivity and solubility. The didehydro and dihydro modifications suggest that the compound has unsaturation and saturation in specific positions of the ring system, affecting its stability and interaction with biological targets. Ergoline derivatives are often studied for their potential pharmacological effects, including interactions with neurotransmitter systems. The specific characteristics, such as melting point, solubility, and biological activity, would require empirical data for precise evaluation, but the structural features suggest potential applications in medicinal chemistry and pharmacology.

Formula: C₁₇H₂₂N₂S

InChI: InChI=1/C17H22N2S/c1-19-9-11(10-20-2)6-14-13-4-3-5-15-17(13)12(8-18-15)7-16(14)19/h3-5,8,11-12,14,16H,6-7,9-10H2,1-2H3

SMILES: CN1CC(CC2c3cccc4c3C(CC12)C=N4)CSC

Pergolide Impurity 7

CAS: 57202-76-3

Formula: C₁₇H₂₂N₂S

Molecular weight: 286.44

Ref: 4Z-P-436008

6-Methyl Pergolide

Controlled Product

CAS: 57202-76-3

Applications 6-Methyl Pergolide is a potent antagonist of 5-HT2A and 5-HT2B receptors on porcine cardiac valves, it also activates brain dopaminergic receptors and lowers cranial DOPAC levels in rats (1,2).
References (1) Fuller, R.W., et al.: Neuroendocrinol., 36, 285 (1983)(2) Goernemann, T., et al.: J. Pharmacol. Exp. Ther., 324, 1136 (2008)

Formula: C₁₇H₂₂N₂S

Color and Shape: Neat

Molecular weight: 286.43

Ref: TR-M326070

Pergolide Impurity 9

CAS: 57202-76-3

Formula: C₁₇H₂₂N₂S

Molecular weight: 286.4

Ref: ST-EA-CP-P166011

LY 116467

CAS: 57202-76-3

LY 116467 is a dopamine agonist.

Formula: C₁₇H₂₂N₂S

Color and Shape: Solid

Molecular weight: 286.43

Ref: TM-T27869