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CAS 57206-54-9

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4-[N-Methyl-4-(methylamino)-L-phenylalanine]virginiamycin S1

Description:
4-[N-Methyl-4-(methylamino)-L-phenylalanine]virginiamycin S1, with the CAS number 57206-54-9, is a semi-synthetic antibiotic derived from the natural product virginiamycin. This compound exhibits characteristics typical of aminoglycoside antibiotics, including a complex structure that allows it to interact with bacterial ribosomes, inhibiting protein synthesis. It is known for its effectiveness against a range of Gram-positive bacteria and some Gram-negative strains, making it valuable in both veterinary and human medicine. The presence of the N-methyl and methylamino groups contributes to its lipophilicity, enhancing its ability to penetrate bacterial membranes. Additionally, its phenylalanine moiety is crucial for its biological activity, as it mimics natural substrates in bacterial metabolism. The compound is typically administered in specific formulations to ensure optimal bioavailability and therapeutic efficacy. Safety and efficacy profiles are well-studied, although, like many antibiotics, it may be associated with resistance development if misused. Overall, this compound represents a significant tool in the fight against bacterial infections.
Formula:C44H52N8O10
InChI:InChI=1/C44H52N8O10/c1-5-30-41(58)51-21-10-13-31(51)42(59)50(4)33(23-26-15-17-28(45-3)18-16-26)43(60)52-22-19-29(53)24-32(52)38(55)49-36(27-11-7-6-8-12-27)44(61)62-25(2)35(39(56)47-30)48-40(57)37-34(54)14-9-20-46-37/h6-9,11-12,14-18,20,25,30-33,35-36,45,54H,5,10,13,19,21-24H2,1-4H3,(H,47,56)(H,48,57)(H,49,55)
Synonyms:
  • Pristinamycin IB
  • RP-13919
  • Vernamycin B&b
  • E-129Z2
  • Ostreogrycin B2
  • Pristinamycin ⅠB
  • Virginiamycin S1, 4-[N-methyl-4-(methylamino)-L-phenylalanine]-
  • 3-Hydroxypicolinoyl-cyclo[L-Thr*-D-Abu-L-Pro-4-methylamino-N-methyl-L-Phe-4-oxo-L-Hpr-L-phenyl Gly-]
  • 4-[N-Methyl-4-(methylamino)-L-phenylalanine]virginiamycin S1
  • See more synonyms
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