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CAS 57224-63-2

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N-Carbobenzyloxy-L-threonine methyl ester

Description:
N-Carbobenzyloxy-L-threonine methyl ester, with the CAS number 57224-63-2, is an amino acid derivative characterized by the presence of a carbobenzyloxy (Cbz) protecting group on the amino group of L-threonine, along with a methyl ester functional group on the carboxylic acid. This compound is typically a white to off-white solid and is soluble in organic solvents such as methanol and dichloromethane, but less soluble in water. The Cbz group serves as a protective moiety, making it useful in peptide synthesis by preventing unwanted reactions at the amino group. The methyl ester enhances the compound's lipophilicity, facilitating its incorporation into various chemical reactions. N-Carbobenzyloxy-L-threonine methyl ester is often utilized in the synthesis of peptides and other bioactive molecules, contributing to research in medicinal chemistry and biochemistry. Its stability under standard laboratory conditions makes it a valuable intermediate in organic synthesis.
Formula:C13H17NO5
InChI:InChI=1/C13H17NO5/c1-9(15)11(12(16)18-2)14-13(17)19-8-10-6-4-3-5-7-10/h3-7,9,11,15H,8H2,1-2H3,(H,14,17)/t9-,11+/m1/s1
Synonyms:
  • Z-Thr-OMe
  • Z-L-Threonine methyl ester
  • methyl N-[(benzyloxy)carbonyl]threoninate
  • methyl N-[(benzyloxy)carbonyl]-L-threoninate
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