CAS 57265-65-3

Calmidazolium chloride

Description:

Calmidazolium chloride is a chemical compound that acts primarily as a calcium/calmodulin-dependent protein kinase inhibitor. It is characterized by its ability to interfere with calcium signaling pathways, making it a valuable tool in biochemical research, particularly in studies related to muscle contraction, neurotransmitter release, and various cellular processes influenced by calcium ions. The compound typically appears as a white to off-white solid and is soluble in water, which facilitates its use in biological assays. Its mechanism of action involves binding to calmodulin, a calcium-binding messenger protein, thereby inhibiting its interaction with target proteins. This inhibition can lead to a range of physiological effects, including modulation of cell growth and differentiation. Due to its specific action on calcium signaling, calmidazolium chloride is often utilized in pharmacological studies and has potential implications in understanding diseases linked to calcium dysregulation. As with any chemical substance, proper handling and safety precautions should be observed, given its biological activity.

Formula: C₃₁H₂₃Cl₆N₂O·Cl

InChI: InChI=1S/C31H23Cl6N2O.ClH/c32-23-6-1-20(2-7-23)31(21-3-8-24(33)9-4-21)39-14-13-38(19-39)17-30(27-12-11-26(35)16-29(27)37)40-18-22-5-10-25(34)15-28(22)36;/h1-16,19,30-31H,17-18H2;1H/q+1;/p-1

InChI key: InChIKey=YGEIMSMISRCBFF-UHFFFAOYSA-M

SMILES: C([N+]1=CN(CC(OCC2=C(Cl)C=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3)C=C1)(C4=CC=C(Cl)C=C4)C5=CC=C(Cl)C=C5.[Cl-]

Synonyms:

• 1-[Bis(4-chlorophenyl)methyl]-3-(2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride)
• 1H-Imidazolium, 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, chloride
• 1H-Imidazolium, 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, chloride (1:1)
• 1H-imidazolium, 3-[bis(4-chlorophenyl)methyl]-1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, chloride (1:1)
• 3-[Bis(4-chlorophenyl)methyl]-1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazol-3-ium chloride
• Calmidazolium chloride
• R 24571

Calmidazolium chloride

CAS: 57265-65-3

Formula: C₃₁H₂₃Cl₇N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 687.6981

Ref: IN-DA00EDRN

Calmidazolium chloride

CAS: 57265-65-3

Calmidazolium chloride

Purity: ≥98%

Molecular weight: 687.7g/mol

Ref: 54-BUP15617

Calmidazolium chloride

CAS: 57265-65-3

Formula: C₃₁H₂₃Cl₇N₂O

Molecular weight: 687.71

Ref: 7W-GL4675

Calmidazolium Chloride

Controlled Product

CAS: 57265-65-3

Formula: C₃₁H₂₃Cl₆N₂O·Cl

Color and Shape: Neat

Molecular weight: 687.698

Ref: TR-C148905

Calmidazolium chloride

CAS: 57265-65-3

Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.

Formula: C₃₁H₂₃Cl₇N₂O

Purity: 98.53%

Color and Shape: Solid

Molecular weight: 687.7

Ref: TM-T10667