CAS 5728-52-9

Felbinac

Description:

Felbinac, with the CAS number 5728-52-9, is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing pain and inflammation. Felbinac is typically administered topically, often in the form of gels or creams, allowing for localized treatment of conditions such as arthritis or muscle pain. The substance is known for its relatively low systemic absorption when applied topically, which minimizes potential side effects associated with oral NSAIDs. Chemically, Felbinac is classified as a benzoic acid derivative, and its structure includes a phenyl group and a carboxylic acid functional group, contributing to its pharmacological activity. While it is effective for pain relief, users should be aware of potential skin irritation or allergic reactions at the application site. Overall, Felbinac serves as a valuable option in the management of localized pain and inflammation.

Formula: C₁₄H₁₂O₂

InChI: InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)

InChI key: InChIKey=QRZAKQDHEVVFRX-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=CC=C(C=C1)C2=CC=CC=C2

Synonyms:

• ([1,1′-Biphenyl]-4-yl)acetic acid
• 2-(4-Phenylphenyl)acetic acid
• 2-(Biphenyl-4-yl)acetic acid
• 2-(Diethylamino)Ethyl 2-Hydroxybiphenyl-3-Carboxylate
• 2-([1,1′-Biphenyl]-4-yl)acetic acid
• 2-Diethylaminoethyl 3-Phenylsalicylate
• 4-Biphenylacetic  biphenyl-4-ylacetic acid
• 4-Biphenylylacetic acid
• 4-Carboxymethylbiphenyl
• 4-Diphenylacetic Acid
• 4-Phenylphenylacetic Acid
• Acetic acid, (4-biphenylyl)-
• Biphenyl-4-Acetic Acid
• Biphenyl-4-Ylacetate
• Biphenyl-4-yl-acetic acid
• Ci 83544
• Cl 83544
• Felbinac
• Felbion 35
• L 141
• Ljc 10141
• Ly 61017
• NSC 16284
• P-Biphenylacetic acid
• Seltouch
• Traxam
• Xenysalate
• [1,1'-Biphenyl]-4-Acetic Acid
• p-Biphenylylacetic acid

4-Biphenylacetic Acid

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 212.25

Ref: 3B-B1278

4-Biphenylacetic acid, 98%

CAS: 5728-52-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₂O₂

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to cream to pale brown

Molecular weight: 212.25

Ref: 02-A11749

FELBINAC CRS

CAS: 5728-52-9

FELBINAC CRS

Formula: C₁₄H₁₂O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 212.2439

Ref: 41-Y0000731

Felbinac

CAS: 5728-52-9

Felbinac

Formula: C₁₄H₁₂O₂

Purity: 100.0%

Color and Shape: Off-White

Molecular weight: 212.08373

Ref: 47-620

4-Biphenylacetic acid

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 212.2439

Ref: IN-DA0033X1

Felbinac

CAS: 5728-52-9

Felbinac (Dapson), a topical medicine, is an active metabolite of fenbufen. Felbinac is belonging to the family of NSAIDs of the arylpropionic acid class.

Formula: C₁₄H₁₂O₂

Purity: 99.47%

Color and Shape: Beige Beige Powder

Molecular weight: 212.24

Ref: TM-T0888

Felbinac

CAS: 5728-52-9

Felbinac

Purity: ≥98%

Molecular weight: 212.24g/mol

Ref: 54-BUP18427

(Biphenyl-4-yl)acetic acid

CAS: 5728-52-9

(Biphenyl-4-yl)acetic acid

Formula: C₁₄H₁₂O₂

Purity: 97%

Color and Shape: Off-White Powder

Molecular weight: 212.24388g/mol

Ref: 54-OR5992

4-Biphenylacetic acid

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Purity: (Titration) ≥ 98.0%

Color and Shape: White to off-white or pale yellow-orange powder or crystals

Molecular weight: 212.25

Ref: 7W-GK8159

Felbinac

Controlled Product

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Color and Shape: Neat

Molecular weight: 212.24

Ref: 86-MM3501.00

4-Biphenylacetic Acid

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Molecular weight: 212.25

Ref: 4Z-B-097049

Felbinac

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Color and Shape: Off-White

Molecular weight: 212.24

Ref: TR-F231100

Felbinac

CAS: 5728-52-9

Felbinac is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties. It is a racemic mixture of the enantiomers R-(+)-felbinac and S-(-)-felbinac. The chemical structure of felbinac is similar to that of aspirin, but it has a lower level of side effects. Felbinac inhibits prostaglandin synthesis by blocking cyclooxygenase and lipoxygenase reactions. It also has anti-inflammatory activity, and reduces the production of pro-inflammatory mediators such as PGE2 levels in human serum, which may be due to its ability to inhibit signal pathways in the cell nucleus.
A number of toxicological studies have been conducted using felbinac on rats, mice, rabbits, and dogs. No major toxicological effects were observed at doses up to 1000 mg/kg body weight for 28 days.

Formula: C₁₄H₁₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 212.24 g/mol

Ref: 3D-FF23234

4-Biphenylacetic acid

CAS: 5728-52-9

Formula: C₁₄H₁₂O₂

Purity: 95%

Color and Shape: Solid, White crystalline powder

Molecular weight: 212.248

Ref: 10-F018235