CAS: 572924-54-0 - Deforolimus

Formula: C₅₃H₈₄NO₁₄P

InChI: InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61,67-40)50(58)51(59)54-25-17-16-20-41(54)52(60)66-45(35(4)28-39-22-24-43(46(29-39)64-9)68-69(11,12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15,18-19,27,32,34-36,38-41,43-46,48-49,57,61H,16-17,20-26,28-31H2,1-12H3/b15-13+,18-14+,33-19+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1

InChI key: InChIKey=BUROJSBIWGDYCN-GAUTUEMISA-N

SMILES: O=C1OC(CC(=O)C(C=C(C)C(O)C(OC)C(=O)C(C)CC(C=CC=CC=C(C)C(OC)CC2OC(O)(C(=O)C(=O)N3CCCCC13)C(C)CC2)C)C)C(C)CC4CCC(OP(=O)(C)C)C(OC)C4

Synonyms:

• 42-(Dimethylphosphinate)rapamycin
• Ap 2357
• Ap 23573
• Mk 8669
• Rapamycin, 42-(dimethylphosphinate)
• Ridaforolimus

Ridaforolimus

CAS: 572924-54-0

Ridaforolimus (AP23573), a rapamycin analogue, inhibits mTOR to potentially arrest tumor growth/proliferation via PI3K/Akt pathway.

• Formula: C₅₃H₈₄NO₁₄P
• Purity: 90.00% - 98.55%
• Color and Shape: Off-White Solid
• Molecular weight: 990.21

Ridaforolimus, >80%

CAS: 572924-54-0

Applications An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may …

• Formula: C₅₃H₈₄NO₁₄P
• Purity: >80%
• Color and Shape: Neat
• Molecular weight: 990.21

Deforolimus

CAS: 572924-54-0

mTOR inhibitor; anti-tumoral

• Formula: C₅₃H₈₄NO₁₄P
• Purity: Min. 95%
• Molecular weight: 990.21 g/mol