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CAS 57296-03-4

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di(N-succinimidyl) oxalate

Description:
Di(N-succinimidyl) oxalate, with the CAS number 57296-03-4, is a chemical compound commonly used as a crosslinking agent in bioconjugation and protein chemistry. It features two succinimidyl groups attached to an oxalate moiety, which enhances its reactivity towards amine groups in proteins and other biomolecules. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Its primary application lies in the formation of stable conjugates, facilitating the attachment of various biomolecules, including peptides and antibodies, for research and therapeutic purposes. The succinimidyl groups allow for selective coupling, making it a valuable tool in the development of targeted drug delivery systems and diagnostic assays. However, care must be taken when handling this compound, as it can be sensitive to moisture and may require specific storage conditions to maintain its stability and reactivity.
Formula:C10H8N2O8
InChI:InChI=1/C10H8N2O8/c13-5-1-2-6(14)11(5)19-9(17)10(18)20-12-7(15)3-4-8(12)16/h1-4H2
SMILES:C1CC(=O)N(C1=O)OC(=O)C(=O)ON1C(=O)CCC1=O
Synonyms:
  • oxalic acid bis(N-hydroxysuccinimide)*ester
  • 1,1'-[(1,2-Dioxoethane-1,2-Diyl)Bis(Oxy)]Dipyrrolidine-2,5-Dione
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