CAS 57333-96-7

Tacalcitol

Description:

Tacalcitol, with the CAS number 57333-96-7, is a synthetic derivative of vitamin D3, specifically designed for topical application in the treatment of psoriasis and other skin disorders. It functions primarily as a vitamin D analog, promoting the regulation of skin cell growth and differentiation. Tacalcitol exhibits anti-proliferative effects on keratinocytes, which are the predominant cell type in the epidermis, thereby helping to reduce the excessive scaling and inflammation associated with psoriasis. The compound is typically formulated as a cream or ointment for direct application to affected areas. Its mechanism of action involves binding to vitamin D receptors, leading to modulation of gene expression related to skin cell turnover. Tacalcitol is generally well-tolerated, with a low incidence of side effects, although local irritation may occur in some patients. As with any medication, it is important to use tacalcitol under the guidance of a healthcare professional to ensure safety and efficacy in treatment.

Formula: C₂₇H₄₄O₃

InChI: InChI=1/C27H44O3/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,24)5)9-10-21-15-22(28)16-26(30)19(21)4/h9-10,17-18,22-26,28-30H,4,6-8,11-16H2,1-3,5H3/b20-9+,21-10-/t18-,22-,23-,24+,25-,26+,27-/m1/s1

InChI key: InChIKey=BJYLYJCXYAMOFT-RSFVBTMBSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CC[C@H](C(C)C)O)C)[H])[H]

Synonyms:

• (+)-(5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,24-triol
• (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
• (1S,3R,5Z,7E,24R)-9,10-Secocholesta-5,7,10-trien-1,3,24-triol
• (1S,3R,5Z,7E,24R)-9,10-Secocholesta-5,7,10-triene-1,3,24-triol
• (1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
• 1,3-cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,4R)-4-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
• 1a,24(R)-Dihydroxycholecalciferol
• 1a,24R-Dihydroxyvitamin D3
• 1α,24R-Dihydroxyvitamin D₃
• 57333-96-7
• 9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol, (1α,3β,5Z,7E,24R)-
• Bonalfa
• Curatoderm
• Pri 2191
• Tv 02
• trans-Calcitriol
• (1α，3β-5Z，7E，24R)-9，10-Secoholesta-5，7，10(19)-triene-1，3，24-triol
• lα，24-Dihydroxycholecalciferol
• lα，24R-Dihy-droxyvitamin D3
• 1a,24(R)-Dihydroxyvitamin D3
• Tacalcitol
• [5Z,7E,24R,(+)]-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,24-triol
• 9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol, (1a,3b,5Z,7E,24R)-(9CI)
• 1-alpha-3-beta-5E,7E,24R)-9,10-Secocholesta-5,7,10,19-triene-1,3,24-triol
• 1ALPHA,24(R)-DIHYDROXYVITAMIND3

Tacalcitol

CAS: 57333-96-7

Formula: C₂₇H₄₄O₃

Purity: 98%

Molecular weight: 416.6365

Ref: IN-DA00EBMC

Tacalcitol

CAS: 57333-96-7

Formula: C₂₇H₄₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 416.65

Ref: 4Z-T-165001

Tacalcitol

CAS: 57333-96-7

Molecular weight: 416.64

Ref: 7W-GP2717

Tacalcitol

CAS: 57333-96-7

Vitamin D3 analog; regulates bone development via calcium

Formula: C₂₇H₄₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 416.64 g/mol

Ref: 3D-FT162196

Tacalcitol

CAS: 57333-96-7

Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.

Formula: C₂₇H₄₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 416.64

Ref: TM-T13912