CAS 573675-25-9

5-Bromo-2-cyano-3-nitropyridine

Description:

5-Bromo-2-cyano-3-nitropyridine is a heterocyclic organic compound characterized by its pyridine ring, which is substituted with a bromine atom, a cyano group, and a nitro group. The presence of these functional groups imparts distinct chemical properties to the compound. The bromine atom enhances the compound's reactivity, making it useful in various synthetic applications, particularly in medicinal chemistry and agrochemicals. The cyano group contributes to the compound's polarity and can participate in nucleophilic reactions, while the nitro group is known for its electron-withdrawing properties, influencing the compound's reactivity and stability. This compound is typically a solid at room temperature and may exhibit moderate solubility in polar organic solvents. Its unique structure allows it to serve as a valuable intermediate in the synthesis of more complex molecules, particularly in the development of pharmaceuticals. Safety precautions should be taken when handling this compound, as it may pose health risks due to its reactive nature and potential toxicity.

Formula: C₆H₂BrN₃O₂

InChI: InChI=1/C6H2BrN3O2/c7-4-1-6(10(11)12)5(2-8)9-3-4/h1,3H

SMILES: c1c(cnc(C#N)c1N(=O)=O)Br

Synonyms:

• 5-Bromo-3-nitropyridine-2-carbonitrile
• 5-BROMO-2-CYANO-3-NITROPYRIDINE
• 5-BROMO-3-NITRO-2-CYANOPYRIDINE
• 573675-25-92-PYRIDINECARBONITRILE, 5-BROMO-3-NITRO-
• 2-Cyano-5-bromo-3-nitropyridine
• 5-Bromo-3-nitro-2-cynopyridine

5-Bromo-3-nitropicolinonitrile

CAS: 573675-25-9

Formula: C₆H₂BrN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 228.0030

Ref: IN-DA00371B

5-Bromo-3-nitropyridine-2-carbonitrile

CAS: 573675-25-9

5-Bromo-3-nitropyridine-2-carbonitrile

Formula: C₆H₂BrN₃O₂

Purity: 97%

Color and Shape: grey solid

Molecular weight: 228.00g/mol

Ref: 54-OR8996

5-Bromo-2-cyano-3-nitropyridine

CAS: 573675-25-9

Formula: C₆H₂BrN₃O₂

Purity: ≥ 98.0%

Color and Shape: White to light brown crystalline powder or crystals

Molecular weight: 228.00

Ref: 7W-GK3009

5-Bromo-2-cyano-3-nitropyridine

CAS: 573675-25-9

Formula: C₆H₂BrN₃O₂

Purity: >98.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 228.01

Ref: 3B-B5584

5-Bromo-2-cyano-3-nitropyridine

CAS: 573675-25-9

5-Bromo-2-cyano-3-nitropyridine is a medication that has been shown to be an effective inhibitor of the RET tyrosine kinase. It has been used in clinical studies to treat chronic kidney disease and has been shown to inhibit the growth of cancer cells. The molecular electrostatic potential (MEP) simulations have shown that 5-bromo-2-cyano-3-nitropyridine interacts with the reactive site of RET, inhibiting its function by binding to the nucleophilic substitutions. 5-Bromo-2-cyano-3-nitropyridine is synthesized from 2,5 dibromopyridine and 3 nitrobenzene at high yield. The molecule is chromatographically separated from impurities such as 4 bromo pyridine.

Formula: C₆H₂BrN₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228 g/mol

Ref: 3D-NB67409

5-Bromo-2-cyano-3-nitropyridine

CAS: 573675-25-9

Formula: C₆H₂BrN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 228.005

Ref: 10-F024510